Lactogangliotetraosylceramide

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 598507

CAS#: 107221-01-2

Description: Lactogangliotetraosylceramide is a leukemia-associated antigen having a novel branching structure.


Chemical Structure

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Lactogangliotetraosylceramide
CAS# 107221-01-2

Theoretical Analysis

MedKoo Cat#: 598507
Name: Lactogangliotetraosylceramide
CAS#: 107221-01-2
Chemical Formula: C70H129N3O23
Exact Mass: 1379.9017
Molecular Weight: 1380.8
Elemental Analysis: C, 60.89; H, 9.42; N, 3.04; O, 26.65

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: Lactogangliotetraosylceramide; LcGg4;

IUPAC/Chemical Name: N-((2R,3S,E)-1-(((2R,3S,4R,5R,6R)-5-(((2R,3R,4S,5S,6R)-4-(((2R,3R,4S,5S,6S)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-5-(((2S,3S,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-3-hydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-3,4-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-3-hydroxyoctadec-4-en-2-yl)tetracosanamide

InChi Key: YAVBLHXWKRSXJS-AUHMYXHSSA-N

InChi Code: InChI=1S/C70H129N3O23/c1-5-7-9-11-13-15-17-19-20-21-22-23-24-25-26-28-30-32-34-36-38-40-54(81)73-48(49(80)39-37-35-33-31-29-27-18-16-14-12-10-8-6-2)45-89-69-62(87)61(86)64(52(43-76)92-69)94-70-63(88)66(96-68-56(72-47(4)79)60(85)58(83)51(42-75)91-68)65(53(44-77)93-70)95-67-55(71-46(3)78)59(84)57(82)50(41-74)90-67/h37,39,48-53,55-70,74-77,80,82-88H,5-36,38,40-45H2,1-4H3,(H,71,78)(H,72,79)(H,73,81)/b39-37+/t48-,49+,50-,51+,52-,53-,55+,56-,57-,58-,59-,60+,61-,62+,63-,64+,65+,66+,67+,68-,69-,70-/m1/s1

SMILES Code: O[C@@H]1[C@@H](CO)O[C@@H](O[C@@H]2[C@H]([C@H]([C@H](O[C@@H]2CO)O[C@@H]3[C@H](O)[C@H](O)[C@H](OC[C@H]([C@H](/C=C/CCCCCCCCCCCCC)O)NC(CCCCCCCCCCCCCCCCCCCCCCC)=O)O[C@@H]3CO)O)O[C@@H]4[C@H](NC(C)=O)[C@H](O)[C@H](O)[C@H](CO)O4)[C@@H](NC(C)=O)[C@H]1O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

Preparing Stock Solutions

The following data is based on the product molecular weight 1380.8 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Shigeta K, Ito Y, Ogawa T, Kirihata Y, Hakomori S, Kannagi R. Monoclonal antibodies directed to chemically synthesized lactogangliotetraosylceramide, a leukemia-associated antigen having a novel branching structure. J Biol Chem. 1987 Jan 25;262(3):1358-62. PubMed PMID: 3805024.

2: Levery SB, Holmes EH, Harris DD, Hakomori S. 1H NMR studies of a biosynthetic lacto-ganglio hybrid glycosphingolipid: confirmation of structure, interpretation of "anomalous" chemical shifts, and evidence for interresidue amide-amide hydrogen bonding. Biochemistry. 1992 Feb 4;31(4):1069-80. PubMed PMID: 1310419.