Acetylaleuritolic acid

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 592523

CAS#: 28937-85-1

Description: Acetylaleuritolic acid is an Antitumor agent.


Chemical Structure

img
Acetylaleuritolic acid
CAS# 28937-85-1

Theoretical Analysis

MedKoo Cat#: 592523
Name: Acetylaleuritolic acid
CAS#: 28937-85-1
Chemical Formula: C32H50O4
Exact Mass: 498.3709
Molecular Weight: 498.75
Elemental Analysis: C, 77.06; H, 10.11; O, 12.83

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: NSC 266221; NSC-266221; NSC266221

IUPAC/Chemical Name: (4aS,6bR,8aR,10S,12aR,12bR,14aS,14bS)-10-acetoxy-2,2,6b,9,9,12a,14a-heptamethyl-1,3,4,5,6b,7,8,8a,9,10,11,12,12a,12b,13,14,14a,14b-octadecahydropicene-4a(2H)-carboxylic acid

InChi Key: UROPGAQBZGIPQC-VUHMTIHWSA-N

InChi Code: InChI=1S/C32H50O4/c1-20(33)36-25-12-15-29(6)21(28(25,4)5)9-13-30(7)22(29)10-14-31(8)23(30)11-16-32(26(34)35)18-17-27(2,3)19-24(31)32/h11,21-22,24-25H,9-10,12-19H2,1-8H3,(H,34,35)/t21-,22+,24-,25-,29-,30+,31+,32+/m0/s1

SMILES Code: CC(O[C@H]1CC[C@](C)([C@@H]2[C@@](C3=CC[C@@]4(C(O)=O)CCC(C)(C)C[C@H]4[C@]3(C)CC2)(C)CC5)[C@@H]5C1(C)C)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

Preparing Stock Solutions

The following data is based on the product molecular weight 498.75 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

1: Torrance SJ, Wiedhopf RM, Cole JR. Antitumor agents from Jatropha macrorhiza (Euphorbiaceae) III: acetylaleuritolic acid. J Pharm Sci. 1977 Sep;66(9):1348-9. PubMed PMID: 903883.

2: Zhu CL. [Chemical Constituents from Mallotus paniculatus (II)]. Zhong Yao Cai. 2015 Apr;38(4):764-5. Chinese. PubMed PMID: 26672344.

3: Galarraga Montes E, Amaro-Luis JM. Icosandrin, a novel peltogynoid from the fruits of Phytolacca icosandra (Phytolaccaceae). Nat Prod Res. 2016;30(1):89-94. doi: 10.1080/14786419.2015.1038537. Epub 2015 May 5. PubMed PMID: 25942389.

4: Lima GS, Castro-Pinto DB, Machado GC, Maciel MA, Echevarria A. Antileishmanial activity and trypanothione reductase effects of terpenes from the Amazonian species Croton cajucara Benth (Euphorbiaceae). Phytomedicine. 2015 Nov 15;22(12):1133-7. doi: 10.1016/j.phymed.2015.08.012. Epub 2015 Sep 18. PubMed PMID: 26547537.

5: Li SH, Deng Q, Zhu L, Lai CH, Wang HS, Tan QG. [Terpenoids and sterols from Ricinus communis and their activities against diabetes]. Zhongguo Zhong Yao Za Zhi. 2014 Feb;39(3):448-52. Chinese. PubMed PMID: 24946546.

6: Naengchomnong W, Pinho PM, Kijjoa A, Sawangwong P, Gonzalez MJ, Silva AM, Eaton G, Herz W. Clerodanes and other constituents of Cleidion spiciflorum. Phytochemistry. 2006 May;67(10):1029-33. Epub 2006 May 22. PubMed PMID: 16716368.

7: Tian MQ, Bao GM, Ji NY, Li XM, Wang BG. [Triterpenoids and steroids from Excoecaria agallocha]. Zhongguo Zhong Yao Za Zhi. 2008 Feb;33(4):405-8. Chinese. PubMed PMID: 18533497.

8: Fröhlich JK, Froeder AL, Janovik V, Venturini TP, Pereira RP, Boligon AA, de Brum TF, Alves SH, da Rocha JB, Athayde ML. Antioxidant capacity, antimicrobial activity and triterpenes isolated from Jatropha isabellei Müll Arg. Nat Prod Res. 2013;27(12):1049-59. doi: 10.1080/14786419.2012.706296. Epub 2012 Jul 13. PubMed PMID: 22788721.

9: Souza KM, Guilhon GM, Santos LS, Cascaes MM, Secco RS, Brasil DS, Andrade EH, Marinho PS, Freire LR, Muller AH. Ricinine and other constituents of Aparisthmium cordatum (Euphorbiaceae). Nat Prod Res. 2013 Mar;27(4-5):364-70. doi: 10.1080/14786419.2012.695368. Epub 2012 Jun 18. PubMed PMID: 22708684.

10: Gunasekera SP, Cordell GA, Farnsworth NR. Constituents of Nealchornea yapurenis (Euophorbiaceae). J Nat Prod. 1980 Mar-Apr;43(2):285-7. PubMed PMID: 7381509.

11: Peres MT, Delle Monache F, Cruz AB, Pizzolatti MG, Yunes RA. Chemical composition and antimicrobial activity of Croton urucurana Baillon (Euphorbiaceae). J Ethnopharmacol. 1997 May;56(3):223-6. PubMed PMID: 9201612.

12: Campos MC, Salomão K, Castro-Pinto DB, Leon LL, Barbosa HS, Maciel MA, de Castro SL. Croton cajucara crude extract and isolated terpenes: activity on Trypanosoma cruzi. Parasitol Res. 2010 Oct;107(5):1193-204. doi: 10.1007/s00436-010-1988-6. Epub 2010 Aug 3. PubMed PMID: 20680342.