Lanuginosine

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 598386

CAS#: 23740-25-2

Description: Lanuginosine is an aporphine alkaloid. Lanuginosine exhibited cytotoxicity against U251.


Chemical Structure

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Lanuginosine
CAS# 23740-25-2

Theoretical Analysis

MedKoo Cat#: 598386
Name: Lanuginosine
CAS#: 23740-25-2
Chemical Formula: C18H11NO4
Exact Mass: 305.0688
Molecular Weight: 305.28
Elemental Analysis: C, 70.82; H, 3.63; N, 4.59; O, 20.96

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: Lanuginosine; NSC 137553; NSC-137553; NSC137553; Oxoxylopin; Oxoxylopine;

IUPAC/Chemical Name: 10-methoxy-8H-[1,3]dioxolo[4',5':4,5]benzo[1,2,3-de]benzo[g]quinolin-8-one

InChi Key: WLXLLQQGGGHOMA-UHFFFAOYSA-N

InChi Code: InChI=1S/C18H11NO4/c1-21-10-2-3-11-12(7-10)17(20)16-14-9(4-5-19-16)6-13-18(15(11)14)23-8-22-13/h2-7H,8H2,1H3

SMILES Code: O=C1C2=CC(OC)=CC=C2C3=C4OCOC4=CC5=CC=NC1=C53

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

Preparing Stock Solutions

The following data is based on the product molecular weight 305.28 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Menezes LR, Costa CO, Rodrigues AC, Santo FR, Nepel A, Dutra LM, Silva FM, Soares MB, Barison A, Costa EV, Bezerra DP. Cytotoxic Alkaloids from the Stem of Xylopia laevigata. Molecules. 2016 Jul 8;21(7). pii: E890. doi: 10.3390/molecules21070890. PubMed PMID: 27399666.

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6: Wirasathien L, Pengsuparp T, Moriyasu M, Kawanishi K, Suttisri R. Cytotoxic C-benzylated chalcone and other constituents of Ellipeiopsis cherrevensis. Arch Pharm Res. 2006 Jun;29(6):497-502. PubMed PMID: 16833018.

7: Lu Z, Zhang Q, Chen R, Yu D. [Aporphine alkaloids from branches and leaves of Polyalthia nemoralis]. Zhongguo Zhong Yao Za Zhi. 2009 Sep;34(18):2343-5. Chinese. PubMed PMID: 20030084.

8: Zhang Z, ElSohly HN, Jacob MR, Pasco DS, Walker LA, Clark AM. New sesquiterpenoids from the root of Guatteria multivenia. J Nat Prod. 2002 Jun;65(6):856-9. PubMed PMID: 12088427.

9: Soni VK, Yadav DK, Bano N, Dixit P, Pathak M, Maurya R, Sahai M, Jain SK, Misra-Bhattacharya S. N-Methyl-6, 7-dimethoxyisoquinolone in Annona squamosa twigs is the major immune modifier to elicit polarized Th1 immune response in BALB/c mice. Fitoterapia. 2012 Jan;83(1):110-6. doi: 10.1016/j.fitote.2011.09.019. Epub 2011 Oct 8. PubMed PMID: 22004725.

10: Pyo MK, Yun-Choi HS, Hong YJ. Antiplatelet activities of aporphine alkaloids isolated from leaves of Magnolia obovata. Planta Med. 2003 Mar;69(3):267-9. PubMed PMID: 12677533.