WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 592501
CAS#: 54-80-8
Description: Pronetalol is a non-selective beta blocker.
MedKoo Cat#: 592501
Name: Pronetalol
CAS#: 54-80-8
Chemical Formula: C15H19NO
Exact Mass: 229.1467
Molecular Weight: 229.32
Elemental Analysis: C, 78.56; H, 8.35; N, 6.11; O, 6.98
Synonym: Pronetalol
IUPAC/Chemical Name: 2-Isopropylamino-1-(naphth-2-yl)ethanol
InChi Key: HRSANNODOVBCST-UHFFFAOYSA-N
InChi Code: InChI=1S/C15H19NO/c1-11(2)16-10-15(17)14-8-7-12-5-3-4-6-13(12)9-14/h3-9,11,15-17H,10H2,1-2H3
SMILES Code: CC(NCC(O)C1=CC=C2C=CC=CC2=C1)C
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.03.00
The following data is based on the product molecular weight 229.32 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
1: Black JW, Duncan WA, Shanks RG. Comparison of some properties of pronethalol and propranolol. 1965. Br J Pharmacol. 2010 Jul;160 Suppl 1:S28-42; discussion S26-7. doi: 10.1111/j.1476-5381.2010.00850.x. PubMed PMID: 20590649; PubMed Central PMCID: PMC2947413.
2: Hollenberg NK. The role of beta-blockers as a cornerstone of cardiovascular therapy. Am J Hypertens. 2005 Dec;18(12 Pt 2):165S-168S. PubMed PMID: 16373194.
