Niloticin

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 598327

CAS#: 115404-57-4

Description: Niloticin is an insecticide for mosquito control from Limonia acidissima L.


Chemical Structure

img
Niloticin
CAS# 115404-57-4

Theoretical Analysis

MedKoo Cat#: 598327
Name: Niloticin
CAS#: 115404-57-4
Chemical Formula: C30H48O3
Exact Mass: 456.36
Molecular Weight: 456.710
Elemental Analysis: C, 78.90; H, 10.59; O, 10.51

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: Niloticin;

IUPAC/Chemical Name: (5R,9S,10S,13S,14S,17S)-17-((2S,4R)-4-((S)-3,3-dimethyloxiran-2-yl)-4-hydroxybutan-2-yl)-4,4,10,13,14-pentamethyl-1,2,4,5,6,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one

InChi Key: GKQMMZUXYRXFOH-SDQXWTQCSA-N

InChi Code: InChI=1S/C30H48O3/c1-18(17-22(31)25-27(4,5)33-25)19-11-15-30(8)21-9-10-23-26(2,3)24(32)13-14-28(23,6)20(21)12-16-29(19,30)7/h9,18-20,22-23,25,31H,10-17H2,1-8H3/t18-,19-,20+,22+,23-,25-,28-,29-,30+/m0/s1

SMILES Code: CC(C)([C@@H]1CC=C2[C@]3(CC[C@H]([C@@]3(CC[C@H]2[C@]1(C)CC4)C)[C@@H](C)C[C@@H](O)[C@H]5C(C)(O5)C)C)C4=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 456.71 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

1: Reegan AD, Gandhi MR, Paulraj MG, Balakrishna K, Ignacimuthu S. Effect of niloticin, a protolimonoid isolated from Limonia acidissima L. (Rutaceae) on the immature stages of dengue vector Aedes aegypti L. (Diptera: Culicidae). Acta Trop. 2014 Nov;139:67-76. doi: 10.1016/j.actatropica.2014.07.002. Epub 2014 Jul 11. Erratum in: Acta Trop. 2014 Dec;140:202-3. PubMed PMID: 25019220.

2: Kiplimo JJ, Shahidul Islam M, Koorbanally NA. Ring A-seco limonoids and flavonoids from the Kenyan Vepris uguenensis Engl. and their antioxidant activity. Phytochemistry. 2012 Nov;83:136-43. doi: 10.1016/j.phytochem.2012.06.025. Epub 2012 Aug 13. PubMed PMID: 22898386.

3: Hisham A, Jayakumar G, Bai A, Fujimoto Y. Beddomeilactone: a new triterpene from Dysoxylum beddomei. Nat Prod Res. 2004 Aug;18(4):329-34. PubMed PMID: 15214485.

4: Liu H, Heilmann J, Rali T, Sticher O. New tirucallane-type triterpenes from Dysoxylum variabile. J Nat Prod. 2001 Feb;64(2):159-63. PubMed PMID: 11429992.

5: Grosvenor SN, Mascoll K, McLean S, Reynolds WF, Tinto WF. Tirucallane, apotirucallane, and octanorapotirucallane triterpenes of Simarouba amara. J Nat Prod. 2006 Sep;69(9):1315-8. PubMed PMID: 16989526.

6: Rodrigues VF, Carmo HM, Braz Filho R, Mathias L, Vieira IJ. Two new terpenoids from Trichilia quadrijuga (Meliaceae). Nat Prod Commun. 2010 Feb;5(2):179-84. PubMed PMID: 20334123.

7: Lien TP, Kamperdick C, Schmidt J, Adam G, Van Sung T. Apotirucallane triterpenoids from Luvunga sarmentosa (Rutaceae). Phytochemistry. 2002 Aug;60(7):747-54. PubMed PMID: 12127593.

8: Esimone CO, Eck G, Duong TN, Uberla K, Proksch P, Grunwald T. Potential anti-respiratory syncytial virus lead compounds from Aglaia species. Pharmazie. 2008 Oct;63(10):768-73. PubMed PMID: 18972843.