WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 598305
CAS#: 141363-91-9
Description: Lanomycin is isolated from Pycnidiophora dispersa; inhibits lanosterol 14alpha-demethylase.
MedKoo Cat#: 598305
Name: Lanomycin
CAS#: 141363-91-9
Chemical Formula: C17H27NO4
Exact Mass: 309.194
Molecular Weight: 309.4
Elemental Analysis: C, 65.99; H, 8.80; N, 4.53; O, 20.68
This product is not in stock, which may be available by custom synthesis.
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Synonym: Lanomycin;
IUPAC/Chemical Name: (2R,3S,4R,5R)-4-methoxy-5-methyl-2-((2E,4E,6E)-octa-2,4,6-trien-2-yl)tetrahydro-2H-pyran-3-yl glycinate
InChi Key: DMLQRXAYJODTLF-XNMVBDESSA-N
InChi Code: InChI=1S/C17H27NO4/c1-5-6-7-8-9-12(2)16-17(22-14(19)10-18)15(20-4)13(3)11-21-16/h5-9,13,15-17H,10-11,18H2,1-4H3/b6-5+,8-7+,12-9+/t13-,15-,16-,17+/m1/s1
SMILES Code: NCC(O[C@@H]1[C@@H](/C(C)=C/C=C/C=C/C)OC[C@@H](C)[C@H]1OC)=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 309.4 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
1: O'Sullivan J, Phillipson DW, Kirsch DR, Fisher SM, Lai MH, Trejo WH. Lanomycin and glucolanomycin, antifungal agents produced by Pycnidiophora dispersa. I. Discovery, isolation and biological activity. J Antibiot (Tokyo). 1992 Mar;45(3):306-12. PubMed PMID: 1577658.
2: Remsburg B, Phillipson DW, O'Sullivan J. Lanomycin and glucolanomycin, antifungal agents produced by Pycnidiophora dispersa. III. Biosynthesis of lanomycin: 13C NMR assignment and origin of the carbon skeleton. J Antibiot (Tokyo). 1992 Mar;45(3):420-3. PubMed PMID: 1577669.
3: Phillipson DW, O'Sullivan J, Johnson JH, Bolgar MS, Kahle AD. Lanomycin and glucolanomycin, antifungal agents produced by Pycnidiophora dispersa. II. Structure elucidation. J Antibiot (Tokyo). 1992 Mar;45(3):313-9. PubMed PMID: 1577659.
