N-Boc-PEG4-bromide
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MedKoo CAT#: 572133

CAS#: 1392499-32-9

Description: N-Boc-PEG4-bromide is a PEG derivative containing a bromide group and Boc-protected amino group. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The Boc group can be deprotected under mild acidic conditions to form the free amine.


Price and Availability

Size Price Shipping out time Quantity
100mg USD 500 Inquiry
250mg USD 830 Inquiry
500mg USD 1230 Inquiry
Inquire bulk and customized quantity

Pricing updated 2020-02-17. Prices are subject to change without notice.

N-Boc-PEG4-bromide, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 572133
Name: N-Boc-PEG4-bromide
CAS#: 1392499-32-9
Chemical Formula: C15H30BrNO6
Exact Mass: 399.1257
Molecular Weight: 400.31
Elemental Analysis: C, 45.01; H, 7.55; Br, 19.96; N, 3.50; O, 23.98


Synonym: N-Boc-PEG4-bromide

IUPAC/Chemical Name: tert-butyl (14-bromo-3,6,9,12-tetraoxatetradecyl)carbamate

InChi Key: KYOVSWOWVSWAII-UHFFFAOYSA-N

InChi Code: InChI=1S/C15H30BrNO6/c1-15(2,3)23-14(18)17-5-7-20-9-11-22-13-12-21-10-8-19-6-4-16/h4-13H2,1-3H3,(H,17,18)

SMILES Code: O=C(OC(C)(C)C)NCCOCCOCCOCCOCCBr


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
2934.99.03.00


References

1: Zhang P, Huang Y, Liu H, Marquez RT, Lu J, Zhao W, Zhang X, Gao X, Li J, Venkataramanan R, Xu L, Li S. A PEG-Fmoc conjugate as a nanocarrier for paclitaxel. Biomaterials. 2014 Aug;35(25):7146-56. doi: 10.1016/j.biomaterials.2014.04.108. Epub 2014 May 22. PubMed PMID: 24856103; PubMed Central PMCID: PMC4102141.

2: Salmaso S, Bersani S, Scomparin A, Mastrotto F, Scherpfer R, Tonon G, Caliceti P. Tailored PEG for rh-G-CSF analogue site-specific conjugation. Bioconjug Chem. 2009 Jun;20(6):1179-85. doi: 10.1021/bc9000432. PubMed PMID: 19469471.