2MeSATP

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 563413

CAS#: 100020-57-3

Description: 2MeSATP is a potent P2y-purine agonist. It acts by half-maximally activating glycogen phosphorylase at 20 nM to be about 25 times more effective than ATP.


Chemical Structure

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2MeSATP
CAS# 100020-57-3

Theoretical Analysis

MedKoo Cat#: 563413
Name: 2MeSATP
CAS#: 100020-57-3
Chemical Formula: C11H14N5Na4O13P3S
Exact Mass:
Molecular Weight: 641.19
Elemental Analysis: C, 20.61; H, 2.20; N, 10.92; Na, 14.34; O, 32.44; P, 14.49; S, 5.00

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: 2MeSATP; 2-MeS-ATP tetrasodium salt; 2 MeS ATP tetrasodium salt; 2-MeS-ATP tetrasodium salt; 2-MeS ATP 4Na salt;

IUPAC/Chemical Name: 2-(Methylthio)adenosine 5'-triphosphate tetrasodium salt

InChi Key: UEEFBRHXFDJPTA-KWIZKVQNSA-J

InChi Code: InChI=1S/C11H18N5O13P3S.4Na/c1-33-11-14-8(12)5-9(15-11)16(3-13-5)10-7(18)6(17)4(27-10)2-26-31(22,23)29-32(24,25)28-30(19,20)21;;;;/h3-4,6-7,10,17-18H,2H2,1H3,(H,22,23)(H,24,25)(H2,12,14,15)(H2,19,20,21);;;;/q;4*+1/p-4/t4-,6-,7-,10-;;;;/m1..../s1

SMILES Code: O[C@@H]([C@H]([C@H](N1C=NC2=C(N=C(SC)N=C21)N)O3)O)[C@H]3COP([O-])(OP([O-])(OP([O-])([O-])=O)=O)=O.[Na+].[Na+].[Na+].[Na+]

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

Preparing Stock Solutions

The following data is based on the product molecular weight 641.19 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Bennett MR. The discovery of a new class of synaptic transmitters in smooth muscle 50 years ago and amelioration of coronary artery thrombosis. Acta Physiol (Oxf). 2013 Feb;207(2):236-43. doi: 10.1111/apha.12039. Epub 2012 Dec 14. Review. PubMed PMID: 23167304.

2: Nicholas RA. Identification of the P2Y(12) receptor: a novel member of the P2Y family of receptors activated by extracellular nucleotides. Mol Pharmacol. 2001 Sep;60(3):416-20. Review. PubMed PMID: 11502870.

3: Pavenstädt H, Henger A, Briner V, Greger R, Schollmeyer P. Extracellular ATP regulates glomerular endothelial cell function. J Auton Pharmacol. 1996 Dec;16(6):389-91. Review. PubMed PMID: 9131423.

4: Lambrecht G. Design and pharmacology of selective P2-purinoceptor antagonists. J Auton Pharmacol. 1996 Dec;16(6):341-4. Review. PubMed PMID: 9131412.

5: Hillaire-Buys D, Chapal J, Bertrand G, Petit P, Loubatières-Mariani MM. Purinergic receptors on insulin-secreting cells. Fundam Clin Pharmacol. 1994;8(2):117-27. Review. PubMed PMID: 8020870.

6: Keppens S. The complex interaction of ATP and UTP with isolated hepatocytes. How many receptors? Gen Pharmacol. 1993 Mar;24(2):283-9. Review. PubMed PMID: 8482512.