WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 563413
Description: 2MeSATP is a potent P2y-purine agonist. It acts by half-maximally activating glycogen phosphorylase at 20 nM to be about 25 times more effective than ATP.
MedKoo Cat#: 563413
Chemical Formula: C11H14N5Na4O13P3S
Molecular Weight: 641.19
Elemental Analysis: C, 20.61; H, 2.20; N, 10.92; Na, 14.34; O, 32.44; P, 14.49; S, 5.00
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.
Synonym: 2MeSATP; 2-MeS-ATP tetrasodium salt; 2 MeS ATP tetrasodium salt; 2-MeS-ATP tetrasodium salt; 2-MeS ATP 4Na salt;
IUPAC/Chemical Name: 2-(Methylthio)adenosine 5'-triphosphate tetrasodium salt
InChi Key: UEEFBRHXFDJPTA-KWIZKVQNSA-J
InChi Code: InChI=1S/C11H18N5O13P3S.4Na/c1-33-11-14-8(12)5-9(15-11)16(3-13-5)10-7(18)6(17)4(27-10)2-26-31(22,23)29-32(24,25)28-30(19,20)21;;;;/h3-4,6-7,10,17-18H,2H2,1H3,(H,22,23)(H,24,25)(H2,12,14,15)(H2,19,20,21);;;;/q;4*+1/p-4/t4-,6-,7-,10-;;;;/m1..../s1
SMILES Code: O[C@@H]([C@H]([C@H](N1C=NC2=C(N=C(SC)N=C21)N)O3)O)[C@H]3COP([O-])(OP([O-])(OP([O-])([O-])=O)=O)=O.[Na+].[Na+].[Na+].[Na+]
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.03.00
The following data is based on the product molecular weight 641.19 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Bennett MR. The discovery of a new class of synaptic transmitters in smooth muscle 50 years ago and amelioration of coronary artery thrombosis. Acta Physiol (Oxf). 2013 Feb;207(2):236-43. doi: 10.1111/apha.12039. Epub 2012 Dec 14. Review. PubMed PMID: 23167304.
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4: Lambrecht G. Design and pharmacology of selective P2-purinoceptor antagonists. J Auton Pharmacol. 1996 Dec;16(6):341-4. Review. PubMed PMID: 9131412.
5: Hillaire-Buys D, Chapal J, Bertrand G, Petit P, Loubatières-Mariani MM. Purinergic receptors on insulin-secreting cells. Fundam Clin Pharmacol. 1994;8(2):117-27. Review. PubMed PMID: 8020870.
6: Keppens S. The complex interaction of ATP and UTP with isolated hepatocytes. How many receptors? Gen Pharmacol. 1993 Mar;24(2):283-9. Review. PubMed PMID: 8482512.