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MedKoo CAT#: 555286

CAS#: 1616413-96-7

Description: UCB9608 is a Potent, Orally Bioavailable PI4KIIIβ Inhibitor. UCB9608 showed the improved metabolic stability and excellent pharmacokinetic profile. UCB9608 is an 11 nM PI4KIIIβ inhibitor that inhibits the HuMLR response with IC50 = 37 nM. Its potency and excellent ADME properties make it an ideal compound for future use as an in vitro and in vivo probe to elucidate the emerging role of PI4KIIIβ inhibition in immune processes.

Price and Availability

Size Price Shipping out time Quantity
100mg USD 850 2 Weeks
200mg USD 1450 2 Weeks
500mg USD 2650 2 Weeks
1g USD 3650 2 Weeks
2g USD 6450 2 Weeks
Inquire bulk and customized quantity

Pricing updated 2020-10-30. Prices are subject to change without notice.

UCB9608, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 555286
Name: UCB9608
CAS#: 1616413-96-7
Chemical Formula: C20H26N8O2
Exact Mass: 410.2179
Molecular Weight: 410.482
Elemental Analysis: C, 58.52; H, 6.38; N, 27.30; O, 7.80

Synonym: UCB9608; UCB-9608; UCB 9608.

IUPAC/Chemical Name: (3S)-4-(6-amino-1-methyl-pyrazolo[3,4-d]pyrimidin-4-yl)-N-(4-methoxy-2-methyl-phenyl)-3-methyl-piperazine-1-carboxamide


InChi Code: InChI=1S/C20H26N8O2/c1-12-9-14(30-4)5-6-16(12)23-20(29)27-7-8-28(13(2)11-27)18-15-10-22-26(3)17(15)24-19(21)25-18/h5-6,9-10,13H,7-8,11H2,1-4H3,(H,23,29)(H2,21,24,25)/t13-/m0/s1

SMILES Code: O=C(N1C[C@H](C)N(C2=C3C(N(C)N=C3)=NC(N)=N2)CC1)NC4=CC=C(OC)C=C4C

Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1: Reuberson J, Horsley H, Franklin RJ, Ford D, Neuss J, Brookings D, Huang Q,
Vanderhoydonck B, Gao LJ, Jang M, Herdewijn P, Ghawalkar A, Fallah-Arani F, Khan
A, Henshall J, Jairaj M, Malcolm S, Ward E, Shuttleworth L, Lin Y, Li S, Louat T,
Waer M, Herman J, Payne A, Ceska T, Doyle C, Pitt WR, Calmiano M, Augustin M,
Steinbacher S, Lammens A, Allen R. Discovery of a potent, orally bioavailable
PI4KIIIβ inhibitor (UCB9608) able to significantly prolong allogeneic organ
engraftment in vivo. J Med Chem. 2018 Jun 28. doi: 10.1021/acs.jmedchem.8b00521.
[Epub ahead of print] PubMed PMID: 29952567.