Lambertine hydroxide

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 559065

CAS#: 119420-08-5

Description: Lambertine is a bioactive chemical.


Chemical Structure

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Lambertine hydroxide
CAS# 119420-08-5

Theoretical Analysis

MedKoo Cat#: 559065
Name: Lambertine hydroxide
CAS#: 119420-08-5
Chemical Formula: C20H21NO5
Exact Mass: 355.142
Molecular Weight: 355.39
Elemental Analysis: C, 67.59; H, 5.96; N, 3.94; O, 22.51

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: Lambertine hydroxide;

IUPAC/Chemical Name: 9,10-dimethoxy-5,6,8,13-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinolin-7-ium hydroxide

InChi Key: WXKFWDFORAXLOD-UHFFFAOYSA-M

InChi Code: InChI=1S/C20H20NO4.H2O/c1-22-17-4-3-12-7-16-14-9-19-18(24-11-25-19)8-13(14)5-6-21(16)10-15(12)20(17)23-2;/h3-4,8-9H,5-7,10-11H2,1-2H3;1H2/q+1;/p-1

SMILES Code: COc1c(C[N+]2=C(c3cc(OCO4)c4cc3CC2)C5)c5ccc1OC.[OH-]

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

Preparing Stock Solutions

The following data is based on the product molecular weight 355.39 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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Reconstitution Calculator

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1: Forghani M, Mashhoor H, Rouhani A, Jafarzadeh H. Comparison of pH changes induced by calcium enriched mixture and those of calcium hydroxide in simulated root resorption defects. J Endod. 2014 Dec;40(12):2070-3. doi: 10.1016/j.joen.2014.09.006. Epub 2014 Oct 22. PubMed PMID: 25442726.

2: Choi TH, Liang R, Maupin CM, Voth GA. Application of the SCC-DFTB method to hydroxide water clusters and aqueous hydroxide solutions. J Phys Chem B. 2013 May 2;117(17):5165-79. doi: 10.1021/jp400953a. Epub 2013 Apr 22. PubMed PMID: 23566052.

3: Xiong L, Gu S, Jensen KO, Yan YS. Facilitated transport in hydroxide-exchange membranes for post-combustion CO2 separation. ChemSusChem. 2014 Jan;7(1):114-6. doi: 10.1002/cssc.201300286. Epub 2013 Sep 20. PubMed PMID: 24115729.

4: Agmon N, Bakker HJ, Campen RK, Henchman RH, Pohl P, Roke S, Thämer M, Hassanali A. Protons and Hydroxide Ions in Aqueous Systems. Chem Rev. 2016 Jul 13;116(13):7642-72. doi: 10.1021/acs.chemrev.5b00736. Epub 2016 Jun 17. Review. PubMed PMID: 27314430.

5: Okubo A, Obata H, Magara M, Kimura T, Ogawa H. Rapid collection of iron hydroxide for determination of Th isotopes in seawater. Anal Chim Acta. 2013 Dec 4;804:120-5. doi: 10.1016/j.aca.2013.10.004. Epub 2013 Oct 12. PubMed PMID: 24267072.

6: Lv F, Xu L, Zhang Y, Meng Z. Layered Double Hydroxide Assemblies with Controllable Drug Loading Capacity and Release Behavior as well as Stabilized Layer-by-Layer Polymer Multilayers. ACS Appl Mater Interfaces. 2015 Sep 2;7(34):19104-11. doi: 10.1021/acsami.5b04569. Epub 2015 Aug 27. PubMed PMID: 26237052.

7: Yosca TH, Rittle J, Krest CM, Onderko EL, Silakov A, Calixto JC, Behan RK, Green MT. Iron(IV)hydroxide pK(a) and the role of thiolate ligation in C-H bond activation by cytochrome P450. Science. 2013 Nov 15;342(6160):825-9. doi: 10.1126/science.1244373. PubMed PMID: 24233717; PubMed Central PMCID: PMC4299822.

8: Bankura A, Chandra A. Hydroxide ion can move faster than an excess proton through one-dimensional water chains in hydrophobic narrow pores. J Phys Chem B. 2012 Aug 16;116(32):9744-57. doi: 10.1021/jp301466e. Epub 2012 Aug 7. PubMed PMID: 22793519.

9: Littlefield BT, Weller MT. Lightweight nanoporous metal hydroxide-rich zeotypes. Nat Commun. 2012;3:1114. doi: 10.1038/ncomms2129. PubMed PMID: 23047672.

10: Soniat M, Kumar R, Rick SW. Hydrated proton and hydroxide charge transfer at the liquid/vapor interface of water. J Chem Phys. 2015 Jul 28;143(4):044702. doi: 10.1063/1.4926831. PubMed PMID: 26233152.

11: Zancan RF, Vivan RR, Milanda Lopes MR, Weckwerth PH, de Andrade FB, Ponce JB, Duarte MA. Antimicrobial Activity and Physicochemical Properties of Calcium Hydroxide Pastes Used as Intracanal Medication. J Endod. 2016 Dec;42(12):1822-1828. doi: 10.1016/j.joen.2016.08.017. Epub 2016 Oct 21. PubMed PMID: 27776884.

12: Wu Y, Zhu R, Ge X, Sun X, Wang Z, Wang W, Wang M, Liu H, Wang S. Size-dependent effects of layered double hydroxide nanoparticles on cellular functions of mouse embryonic stem cells. Nanomedicine (Lond). 2015;10(23):3469-82. doi: 10.2217/nnm.15.158. Epub 2015 Nov 26. PubMed PMID: 26607261.

13: Khong TT, Aachmann FL, Vårum KM. Kinetics of de-N-acetylation of the chitin disaccharide in aqueous sodium hydroxide solution. Carbohydr Res. 2012 May 1;352:82-7. doi: 10.1016/j.carres.2012.01.028. Epub 2012 Feb 10. PubMed PMID: 22424830.

14: Shi W, Jia Y, Xu S, Li Z, Fu Y, Wei M, Shi S. A chiroptical switch based on DNA/layered double hydroxide ultrathin films. Langmuir. 2014 Nov 4;30(43):12916-22. doi: 10.1021/la502968z. Epub 2014 Oct 20. PubMed PMID: 25285378.

15: Falzone AJ, Nguyen J, Weare WW, Sommer RD, Boyle PD. An unsupported metal hydroxide for the design of molecular μ-oxo bridged heterobimetallic complexes. Chem Commun (Camb). 2014 Feb 28;50(17):2139-41. doi: 10.1039/c3cc49066a. Epub 2014 Jan 14. Erratum in: Chem Commun (Camb). 2014 Aug 28;50(67):9608. PubMed PMID: 24419147.

16: Yao F, Hu H, Xu S, Huo R, Zhao Z, Zhang F, Xu F. Preparation and regulating cell adhesion of anion-exchangeable layered double hydroxide micropatterned arrays. ACS Appl Mater Interfaces. 2015 Feb 25;7(7):3882-7. doi: 10.1021/acsami.5b00145. Epub 2015 Feb 9. PubMed PMID: 25654314.

17: Zhu Y, Wu Y, Zhang H, Wang Z, Wang S, Qian Y, Zhu R. Enhanced Anti-Metastatic Activity of Etoposide Using Layered Double Hydroxide Nano Particles. J Biomed Nanotechnol. 2015 Dec;11(12):2158-68. PubMed PMID: 26510310.

18: Xie Y, Luk HL, Yang X, Glusac KD. Excited-state hydroxide ion transfer from a model xanthenol photobase. J Phys Chem B. 2015 Feb 12;119(6):2498-506. doi: 10.1021/jp5080169. Epub 2014 Nov 11. PubMed PMID: 25347397.

19: Tammaro L, Vittoria V, Calarco A, Petillo O, Riccitiello F, Peluso G. Effect of layered double hydroxide intercalated with fluoride ions on the physical, biological and release properties of a dental composite resin. J Dent. 2014 Jan;42(1):60-7. doi: 10.1016/j.jdent.2013.10.019. Epub 2013 Nov 13. PubMed PMID: 24239926.

20: Sun X, Dey SK. Insights into the synthesis of layered double hydroxide (LDH) nanoparticles: Part 2. Formation mechanisms of LDH. J Colloid Interface Sci. 2015 Nov 15;458:160-8. doi: 10.1016/j.jcis.2015.06.025. Epub 2015 Jun 25. PubMed PMID: 26218195; PubMed Central PMCID: PMC4706762.