Aminometradine

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 592430

CAS#: 642-44-4

Description: Aminometradine is a diuretic agent.


Chemical Structure

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Aminometradine
CAS# 642-44-4

Theoretical Analysis

MedKoo Cat#: 592430
Name: Aminometradine
CAS#: 642-44-4
Chemical Formula: C9H13N3O2
Exact Mass: 195.1008
Molecular Weight: 195.22
Elemental Analysis: C, 55.37; H, 6.71; N, 21.52; O, 16.39

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: Aminometradine; Aminometramide; BRN 0175533; Catapyrin

IUPAC/Chemical Name: 1-Allyl-6-amino-3-ethyluracil

InChi Key: NGXUUAFYUCOICP-UHFFFAOYSA-N

InChi Code: InChI=1S/C9H13N3O2/c1-3-5-12-7(10)6-8(13)11(4-2)9(12)14/h3,6H,1,4-5,10H2,2H3

SMILES Code: O=C(N1CC)N(CC=C)C(N)=CC1=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

Preparing Stock Solutions

The following data is based on the product molecular weight 195.22 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

Molarity Calculator

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Reconstitution Calculator

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Dilution Calculator

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1: NIELSEN OE. Comparative studies of the diuretics acetazolamide, aminometradine, chlorothiazide and theophylline. Acta Pharmacol Toxicol (Copenh). 1961;18:23-37. PubMed PMID: 13728955.

2: FORD RV, MOYER JH, HANDLEY CA, SPURR CL, ROCHELLE JB 3rd. Laboratory and clinical observations on three similar diuretic agents: aminophylline, aminometradine (mictine) and aminoisometradine (rolicton). Am J Med Sci. 1957 Dec;234(6):640-55. PubMed PMID: 13487573.

3: WATSON DD, BALFOUR DC Jr. Use of the oral diuretics, aminometradine and aminoisometradine, in the sodium and water retention of hepatic cirrhosis. Gastroenterology. 1957 Aug;33(2):202-8. PubMed PMID: 13462067.

4: HANLEY T. Current therapeutics. CVIII. Aminometradine. Practitioner. 1956 Dec;177(1062):744-9. PubMed PMID: 13389104.

5: AMINOMETRADINE. J Am Med Assoc. 1956 Sep 8;162(2):116. PubMed PMID: 13357301.

6: PLATTS MM, HANLEY T. Aminometradine in treatment of congestive heart failure. Br Med J. 1956 May 12;1(4975):1078-80. PubMed PMID: 13316073; PubMed Central PMCID: PMC1979900.