Marasmic acid

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 598198

CAS#: 2212-99-9

Description: Marasmic acid is an antifungal bioactive chemical.


Chemical Structure

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Marasmic acid
CAS# 2212-99-9

Theoretical Analysis

MedKoo Cat#: 598198
Name: Marasmic acid
CAS#: 2212-99-9
Chemical Formula: C15H18O4
Exact Mass: 262.12
Molecular Weight: 262.300
Elemental Analysis: C, 68.69; H, 6.92; O, 24.40

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: Marasmic acid; NSC 318506; NSC-318506; NSC318506; LACHNELLA FUNGUS; CCRIS 1701;

IUPAC/Chemical Name: (3S,3aR,5aR,8aS,8bS)-3-hydroxy-7,7-dimethyl-1-oxo-5a,7,8,8a-tetrahydro-1H,3H,6H-3a,8b-methanoindeno[4,5-c]furan-4-carbaldehyde

InChi Key: BIUVCPLWWOLECJ-TVXZTZGSSA-N

InChi Code: InChI=1S/C15H18O4/c1-13(2)4-8-3-9(6-16)14-7-15(14,10(8)5-13)12(18)19-11(14)17/h3,6,8,10-11,17H,4-5,7H2,1-2H3/t8-,10-,11-,14-,15+/m0/s1

SMILES Code: O=CC1=C[C@@H]2[C@H](CC(C)(C2)C)[C@@]3([C@]1(C3)[C@H](O4)O)C4=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 262.30 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Jacob S, Schüffler A, Thines E. Hog1p activation by marasmic acid through inhibition of the histidine kinase Sln1p. Pest Manag Sci. 2016 Jun;72(6):1268-74. doi: 10.1002/ps.4257. Epub 2016 Mar 22. PubMed PMID: 26888741; PubMed Central PMCID: PMC5071701.

2: Kupka J, Anke T, Mizumoto K, Giannetti BM, Steglich W. Antibiotics from basidiomycetes. XVII. The effect of marasmic acid on nucleic acid metabolism. J Antibiot (Tokyo). 1983 Feb;36(2):155-60. PubMed PMID: 6300012.

3: DUGAN JJ, DE MAYO P, NISBET M, ANCHEL M. MARASMIC ACID. J Am Chem Soc. 1965 Jun 20;87:2768-9. PubMed PMID: 14292180.

4: Dugan JJ, de Mayo P, Nisbet M, Robinson JR, Anchel M. Terpenoids. XIV. The constitution and biogenesis of marasmic acid. J Am Chem Soc. 1966 Jun 20;88(12):2838-44. PubMed PMID: 5941267.

5: Wilson SR, Turner RB. Studies in sesquiterpene synthesis. The marasmic acid skeleton. J Org Chem. 1973 Aug 10;38(16):2870-3. PubMed PMID: 4739032.

6: Heim J, Anke T, Mocek U, Steffan B, Steglich W. Antibiotics from basidiomycetes. XXIX: Pilatin, a new antibiotically active marasmane derivative from cultures of Flagelloscypha pilatii agerer. J Antibiot (Tokyo). 1988 Dec;41(12):1752-7. PubMed PMID: 3209467.