8-Br-cGMP
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 563397

CAS#: 51116-01-9

Description: 8-Br-cGMP is an activator of cGMP-dependent protein kinase. It acts by inhibiting the intracellular calcium oscillations of tracheal smooth muscle cells in response to acetylcholine.


Chemical Structure

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8-Br-cGMP
CAS# 51116-01-9

Theoretical Analysis

MedKoo Cat#: 563397
Name: 8-Br-cGMP
CAS#: 51116-01-9
Chemical Formula: C10H10BrN5NaO7P
Exact Mass: 444.9399
Molecular Weight: 446.08
Elemental Analysis: C, 26.93; H, 2.26; Br, 17.91; N, 15.70; Na, 5.15; O, 25.11; P, 6.94

Price and Availability

Size Price Availability Quantity
10.0mg USD 230.0 2 Weeks
25.0mg USD 400.0 2 Weeks
50.0mg USD 660.0 2 Weeks
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Synonym: 8-Br-cGMP; 8 Br cGMP; 8BrcGMP;

IUPAC/Chemical Name: sodium (4aR,6R,7R,7aS)-6-(2-amino-8-bromo-6-oxo-3,6-dihydro-9H-purin-9-yl)-7-hydroxytetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-2-olate 2-oxide

InChi Key: ZJRFCXHKYQVNFK-YEOHUATISA-M

InChi Code: InChI=1S/C10H11BrN5O7P.Na/c11-9-13-3-6(14-10(12)15-7(3)18)16(9)8-4(17)5-2(22-8)1-21-24(19,20)23-5;/h2,4-5,8,17H,1H2,(H,19,20)(H3,12,14,15,18);/q;+1/p-1/t2-,4-,5-,8-;/m1./s1

SMILES Code: [H][C@@]12COP([O-])(O[C@]1([C@H]([C@H](N3C(Br)=NC4=C3NC(N)=NC4=O)O2)O)[H])=O.[Na+]

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

Preparing Stock Solutions

The following data is based on the product molecular weight 446.08 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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