R 59494

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 461071

CAS#: 136917-41-4

Description: R 59494 is a novel anti-ischemic compound.


Chemical Structure

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R 59494
CAS# 136917-41-4

Theoretical Analysis

MedKoo Cat#: 461071
Name: R 59494
CAS#: 136917-41-4
Chemical Formula: C22H23N3OS
Exact Mass: 377.1562
Molecular Weight: 377.5
Elemental Analysis: C, 70.00; H, 6.14; N, 11.13; O, 4.24; S, 8.49

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: R 59494; R-59494; R59494;

IUPAC/Chemical Name: N-methyl-N-(1-(4-phenoxybutyl)-1H-pyrrol-3-yl)benzo[d]thiazol-2-amine

InChi Key: PFBZXLGUUGDBNI-UHFFFAOYSA-N

InChi Code: InChI=1S/C22H23N3OS/c1-24(22-23-20-11-5-6-12-21(20)27-22)18-13-15-25(17-18)14-7-8-16-26-19-9-3-2-4-10-19/h2-6,9-13,15,17H,7-8,14,16H2,1H3

SMILES Code: CN(C1=CN(CCCCOC2=CC=CC=C2)C=C1)C3=NC4=CC=CC=C4S3

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

Preparing Stock Solutions

The following data is based on the product molecular weight 377.5 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

Molarity Calculator

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Reconstitution Calculator

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Dilution Calculator

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1: Wermelskirchen D, Wilffert B, Nebel U, Wirth A, Peters T. Veratridine-induced intoxication in the isolated left atrium of the rat: effects of some anti-ischemic compounds. Naunyn Schmiedebergs Arch Pharmacol. 1991 Jul;344(1):101-6. PubMed PMID: 1663585.

2: Wermelskirchen D, Wilffert B, Nebel U, Leidig A, Wirth A, Peters T. Veratridine activates a silent sodium channel in rat isolated aorta. Eur J Pharmacol. 1992 Aug 25;219(2):253-9. PubMed PMID: 1330608.