MSX-2
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 563386

CAS#: 261717-18-4

Description: MSX-2 is a selective A2A adenosine receptor antagonist.


Chemical Structure

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MSX-2
CAS# 261717-18-4

Theoretical Analysis

MedKoo Cat#: 563386
Name: MSX-2
CAS#: 261717-18-4
Chemical Formula: C21H22N4O4
Exact Mass: 394.1641
Molecular Weight: 394.43
Elemental Analysis: C, 63.95; H, 5.62; N, 14.20; O, 16.22

Price and Availability

Size Price Availability Quantity
5.0mg USD 340.0 2 Weeks
10.0mg USD 560.0 2 Weeks
25.0mg USD 1015.0 2 Weeks
50.0mg USD 2000.0 2 Weeks
100.0mg USD 3000.0 2 Weeks
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Synonym: MSX-2; MSX 2; MSX2;

IUPAC/Chemical Name: 3-(3-Hydroxy-propyl)-8-[2-(3-methoxy-phenyl)-vinyl]-7-methyl-1-prop-2-ynyl-3,7-dihydro-purine-2,6-dione

InChi Key: FWLDDFYHEQMIGG-MDZDMXLPSA-N

InChi Code: InChI=1S/C21H22N4O4/c1-4-11-25-20(27)18-19(24(21(25)28)12-6-13-26)22-17(23(18)2)10-9-15-7-5-8-16(14-15)29-3/h1,5,7-10,14,26H,6,11-13H2,2-3H3/b10-9+

SMILES Code: O=C(N1CC#C)N(CCCO)C2=C(N(C)C(/C=C/C3=CC=CC(OC)=C3)=N2)C1=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

Preparing Stock Solutions

The following data is based on the product molecular weight 394.43 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Becic T, Kero D, Vukojevic K, Mardesic S, Saraga-Babic M. Growth factors FGF8 and FGF2 and their receptor FGFR1, transcriptional factors Msx-1 and MSX-2, and apoptotic factors p19 and RIP5 participate in the early human limb development. Acta Histochem. 2018 Apr;120(3):205-214. doi: 10.1016/j.acthis.2018.01.008. Epub 2018 Feb 4. PubMed PMID: 29409666.

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11: Santerre JL, Nunes EJ, Kovner R, Leser CE, Randall PA, Collins-Praino LE, Lopez Cruz L, Correa M, Baqi Y, Müller CE, Salamone JD. The novel adenosine A(2A) antagonist prodrug MSX-4 is effective in animal models related to motivational and motor functions. Pharmacol Biochem Behav. 2012 Oct;102(4):477-87. doi: 10.1016/j.pbb.2012.06.009. Epub 2012 Jun 15. PubMed PMID: 22705392.

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20: Itaya T, Kagami H, Okada K, Yamawaki A, Narita Y, Inoue M, Sumita Y, Ueda M. Characteristic changes of periodontal ligament-derived cells during passage. J Periodontal Res. 2009 Aug;44(4):425-33. doi: 10.1111/j.1600-0765.2008.01137.x. PubMed PMID: 18973549.

MSX-2

5.0mg / USD 340.0