NF864

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MedKoo CAT#: 558448

CAS#: 69606-09-3

Description: NF864 is a suramin analogue and inhibitor of P2X1 receptors.


Price and Availability

Size Price Shipping out time Quantity
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Pricing updated 2020-10-30. Prices are subject to change without notice.

NF864 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 558448
Name: NF864
CAS#: 69606-09-3
Chemical Formula: C228H148N24Na12O56S12
Exact Mass: 4776.49
Molecular Weight: 4780.4
Elemental Analysis: C, 57.29; H, 3.12; N, 7.03; Na, 5.77; O, 18.74; S, 8.05


Synonym: NF864; NF-864; NF 864;

IUPAC/Chemical Name: 8,8',8'',8'''-(Carbonylbis(imino-5,1,3-benzenetriyl-bis(carbonylimino)))tetrakis-naphthalene-1,3,5-trisulfonic acid dodecasodium salt

InChi Key: PIFHPGCFENMFGY-UHFFFAOYSA-B

InChi Code: InChI=1S/4C57H40N6O14S3.12Na/c4*64-53(60-46-19-7-13-32-10-1-4-16-42(32)46)35-24-36(54(65)61-47-20-8-14-33-11-2-5-17-43(33)47)27-39(26-35)58-57(68)59-40-28-37(55(66)62-48-21-9-15-34-12-3-6-18-44(34)48)25-38(29-40)56(67)63-49-22-23-50(79(72,73)74)45-30-41(78(69,70)71)31-51(52(45)49)80(75,76)77;;;;;;;;;;;;/h4*1-31H,(H,60,64)(H,61,65)(H,62,66)(H,63,67)(H2,58,59,68)(H,69,70,71)(H,72,73,74)(H,75,76,77);;;;;;;;;;;;/q;;;;12*+1/p-12

SMILES Code: O=C(NC1=CC(C(NC2=CC=CC3=CC=CC=C23)=O)=CC(C(NC4=CC=CC5=CC=CC=C45)=O)=C1)NC6=CC(C(NC7=CC=CC8=CC=CC=C78)=O)=CC(C(NC9=CC=C(S(=O)([O-])=O)C%10=CC(S(=O)([O-])=O)=CC(S(=O)([O-])=O)=C9%10)=O)=C6.O=C(NC%11=CC(C(NC%12=CC=CC%13=CC=CC=C%12%13)=O)=CC(C(NC%14=CC=CC%15=CC=CC=C%14%15)=O)=C%11)NC%16=CC(C(NC%17=CC=CC%18=CC=CC=C%17%18)=O)=CC(C(NC%19=CC=C(S(=O)([O-])=O)C%20=CC(S(=O)([O-])=O)=CC(S(=O)([O-])=O)=C%19%20)=O)=C%16.O=C(NC%21=CC(C(NC%22=CC=CC%23=CC=CC=C%22%23)=O)=CC(C(NC%24=CC=CC%25=CC=CC=C%24%25)=O)=C%21)NC%26=CC(C(NC%27=CC=CC%28=CC=CC=C%27%28)=O)=CC(C(NC%29=CC=C(S(=O)([O-])=O)C%30=CC(S(=O)([O-])=O)=CC(S(=O)([O-])=O)=C%29%30)=O)=C%26.O=C(NC%31=CC(C(NC%32=CC=CC%33=CC=CC=C%32%33)=O)=CC(C(NC%34=CC=CC%35=CC=CC=C%34%35)=O)=C%31)NC%36=CC(C(NC%37=CC=CC%38=CC=CC=C%37%38)=O)=CC(C(NC%39=CC=C(S(=O)([O-])=O)C%40=CC(S(=O)([O-])=O)=CC(S(=O)([O-])=O)=C%39%40)=O)=C%36.[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+]


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.03.00


References

1: Horner S, Menke K, Hildebrandt C, Kassack MU, Nickel P, Ullmann H, Mahaut-Smith MP, Lambrecht G. The novel suramin analogue NF864 selectively blocks P2X1 receptors in human platelets with potency in the low nanomolar range. Naunyn Schmiedebergs Arch Pharmacol. 2005 Jul;372(1):1-13. Epub 2005 Sep 13. PubMed PMID: 16158305.