CAUE

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 563352

CAS#: 325148-07-0

Description: CAUE is an inhibitor of telomerase activity in NALM-6 human B-cell leukemia cells.


Chemical Structure

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CAUE
CAS# 325148-07-0

Theoretical Analysis

MedKoo Cat#: 563352
Name: CAUE
CAS#: 325148-07-0
Chemical Formula: C20H30O4
Exact Mass: 334.2144
Molecular Weight: 334.45
Elemental Analysis: C, 71.82; H, 9.04; O, 19.13

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: CAUE;

IUPAC/Chemical Name: Caffeic acid undecyl ester

InChi Key: DIAOJQJAZSZGDC-WYMLVPIESA-N

InChi Code: InChI=1S/C20H30O4/c1-2-3-4-5-6-7-8-9-10-15-24-20(23)14-12-17-11-13-18(21)19(22)16-17/h11-14,16,21-22H,2-10,15H2,1H3/b14-12+

SMILES Code: OC1=CC(/C=C/C(OCCCCCCCCCCC)=O)=CC=C1O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

Preparing Stock Solutions

The following data is based on the product molecular weight 334.45 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Aboarrage Junior AM, Teixeira CVE, Santos RN, Machado AF, Evangelista AL, Rica RL, Alonso AC, Serra AJ, Barroso JA, Baker JS, Bocalini DS. A high-intensity jump-based aquatic exercise program improves bone mineral density and functional fitness in postmenopausal women. Rejuvenation Res. 2018 Jun 11. doi: 10.1089/rej.2018.2069. [Epub ahead of print] PubMed PMID: 29886815.

2: Gomes CJS, Rodrigues BA, Endo I. Analog Models of Flanking Structures and a Natural Example in the Quadrilátero Ferrífero, Minas Gerais. An Acad Bras Cienc. 2017 Jul-Sep;89(3):1431-1442. doi: 10.1590/0001-3765201720160360. Epub 2017 Jul 31. PubMed PMID: 28767888.

3: Borlina CS, Rennó NO. The Impact of a Severe Drought on Dust Lifting in California's Owens Lake Area. Sci Rep. 2017 May 11;7(1):1784. doi: 10.1038/s41598-017-01829-7. PubMed PMID: 28496140; PubMed Central PMCID: PMC5431890.

4: Tomizawa A, Kanno SI, Osanai Y, Yomogida S, Ishikawa M. Cytotoxic effects of caffeic acid undecyl ester are involved in the inhibition of telomerase activity in NALM-6 human B-cell leukemia cells. Oncol Lett. 2013 Oct;6(4):875-877. Epub 2013 Jul 23. PubMed PMID: 24137428; PubMed Central PMCID: PMC3796413.

5: Tomizawa A, Kanno S, Osanai Y, Goto A, Sato C, Yomogida S, Ishikawa M. Induction of apoptosis by a potent caffeic acid derivative, caffeic acid undecyl ester, is mediated by mitochondrial damage in NALM-6 human B cell leukemia cells. Oncol Rep. 2013 Feb;29(2):425-9. doi: 10.3892/or.2012.2163. Epub 2012 Dec 3. PubMed PMID: 23229564; PubMed Central PMCID: PMC3583534.

6: Ramirez LF, Pereira A, Chiriac AM, Bonnet-Boyer MC, Demoly P. Negative predictive value of skin tests to neuromuscular blocking agents. Allergy. 2012 Mar;67(3):439-41. doi: 10.1111/j.1398-9995.2011.02753.x. Epub 2011 Dec 16. PubMed PMID: 22171590.

7: Andersson C, Weeke P, Pecini R, Kjaergaard J, Hassager C, Køber L, Torp-Pedersen C. Long-term impact of diabetes in patients hospitalized with ischemic and non-ischemic heart failure. Scand Cardiovasc J. 2010 Feb;44(1):37-44. doi: 10.3109/14017430903312438. PubMed PMID: 19878095.

8: Ribeiro C, Barrado CM, de Camargo ER, Longo E, Leite ER. Phase transformation in titania nanocrystals by the oriented attachment mechanism: the role of the pH value. Chemistry. 2009;15(9):2217-22. doi: 10.1002/chem.200801019. PubMed PMID: 19142942.

9: Ribeiro C, Vila C, Milton Elias de Matos J, Bettini J, Longo E, Leite ER. Role of the oriented attachment mechanism in the phase transformation of oxide nanocrystals. Chemistry. 2007;13(20):5798-803. PubMed PMID: 17443834.

10: Halenda RM, Primakoff P, Myles DG. Actin filaments, localized to the region of the developing acrosome during early stages, are lost during later stages of guinea pig spermiogenesis. Biol Reprod. 1987 Mar;36(2):491-9. PubMed PMID: 2437971.

11: Nemoy NJ, Fichman MP, Sellers A. Unilateral ureteral obstruction. A caue of reversible high renin content hypertension. JAMA. 1973 Jul 30;225(5):512-3. PubMed PMID: 4351750.

12: La Touche CJ, Tyagi SC, Gentles JC. [Some mycologic and histologic data apropos of 2 cases of maduromycosis caue b Madurella grisea from the Caribbean Isles]. Bull Soc Pathol Exot Filiales. 1967 Jan-Feb;60(1):9-12. French. PubMed PMID: 5631028.