WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 598031

CAS#: 117667-25-1

Description: Lactoferroxin-A is an opioid antagonist.

Chemical Structure

CAS# 117667-25-1

Theoretical Analysis

MedKoo Cat#: 598031
Name: Lactoferroxin-A
CAS#: 117667-25-1
Chemical Formula: C32H44N6O10
Exact Mass: 672.3119
Molecular Weight: 672.73
Elemental Analysis: C, 57.13; H, 6.59; N, 12.49; O, 23.78

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: Lactoferroxin-A; Lactoferroxin A; Tyr-leu-gly-ser-gly-tyr-och3;

IUPAC/Chemical Name: methyl L-tyrosyl-L-leucylglycyl-L-serylglycyl-L-tyrosinate


InChi Code: InChI=1S/C32H44N6O10/c1-18(2)12-24(38-29(44)23(33)13-19-4-8-21(40)9-5-19)30(45)34-16-28(43)37-26(17-39)31(46)35-15-27(42)36-25(32(47)48-3)14-20-6-10-22(41)11-7-20/h4-11,18,23-26,39-41H,12-17,33H2,1-3H3,(H,34,45)(H,35,46)(H,36,42)(H,37,43)(H,38,44)/t23-,24-,25-,26-/m0/s1

SMILES Code: OC1=CC=C(C=C1)C[C@@H](C(OC)=O)NC(CNC([C@H](CO)NC(CNC([C@H](CC(C)C)NC([C@H](CC2=CC=C(O)C=C2)N)=O)=O)=O)=O)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

Preparing Stock Solutions

The following data is based on the product molecular weight 672.73 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Tani F, Iio K, Chiba H, Yoshikawa M. Isolation and characterization of opioid antagonist peptides derived from human lactoferrin. Agric Biol Chem. 1990 Jul;54(7):1803-10. PubMed PMID: 1369293.

2: Patten GS, Head RJ, Abeywardena MY. Effects of casoxin 4 on morphine inhibition of small animal intestinal contractility and gut transit in the mouse. Clin Exp Gastroenterol. 2011;4:23-31. doi: 10.2147/CEG.S16161. Epub 2011 Feb 10. PubMed PMID: 21694869; PubMed Central PMCID: PMC3108675.

3: Iwan M, Jarmołowska B, Bielikowicz K, Kostyra E, Kostyra H, Kaczmarski M. Transport of micro-opioid receptor agonists and antagonist peptides across Caco-2 monolayer. Peptides. 2008 Jun;29(6):1042-7. doi: 10.1016/j.peptides.2008.01.018. Epub 2008 Feb 6. PubMed PMID: 18355944.