WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 592280

CAS#: 146-80-5

Description: Xanthosine treatment has been demonstrated to promote expansion of putative mammary stem cells. Xanthosine treatment also increased the proliferation rate of bovine MEC in vitro

Chemical Structure

CAS# 146-80-5

Theoretical Analysis

MedKoo Cat#: 592280
Name: Xanthosine
CAS#: 146-80-5
Chemical Formula: C10H12N4O6
Exact Mass: 284.08
Molecular Weight: 284.230
Elemental Analysis: C, 42.26; H, 4.26; N, 19.71; O, 33.77

Price and Availability

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100g USD 230
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Synonym: Xanthosine; NSC 18930; NSC-18930; NSC18930

IUPAC/Chemical Name: 9-beta-D-Ribofuranosylxanthine


InChi Code: InChI=1S/C10H12N4O6/c15-1-3-5(16)6(17)9(20-3)14-2-11-4-7(14)12-10(19)13-8(4)18/h2-3,5-6,9,15-17H,1H2,(H2,12,13,18,19)/t3-,5-,6-,9-/m1/s1

SMILES Code: OC[C@@H]1[C@H]([C@H]([C@H](N2C=NC3=C(N=C(N=C32)O)O)O1)O)O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 284.23 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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7: Li H, Zhang X, Zhang L, Cheng W, Kong F, Fan D, Li L, Wang W. Silica stationary phase functionalized by 4-carboxy-benzoboroxole with enhanced boronate affinity nature for selective capture and separation of cis-diol compounds. Anal Chim Acta. 2017 Sep 8;985:91-100. doi: 10.1016/j.aca.2017.07.006. Epub 2017 Jul 12. PubMed PMID: 28864199.

8: Zhou J, Lu C, Zhang D, Ma C, Su X. NMR-based metabolomics reveals the metabolite profiles of Vibrio parahaemolyticus under ferric iron stimulation. J Microbiol. 2017 Aug;55(8):628-634. doi: 10.1007/s12275-017-6551-z. Epub 2017 Jul 28. PubMed PMID: 28752295.

9: Anthony S, Peterson JR, Ji Y. Use of Inosine Monophosphate Dehydrogenase Activity Assay to Determine the Specificity of PARP-1 Inhibitors. Methods Mol Biol. 2017;1608:337-342. doi: 10.1007/978-1-4939-6993-7_22. PubMed PMID: 28695520.

10: Kumar A, Naik GK, Giridhar P. Dataset on exogenous application of salicylic acid and methyljasmonate and the accumulation of caffeine in young leaf tissues and catabolically inactive endosperms. Data Brief. 2017 May 10;13:22-27. doi: 10.1016/j.dib.2017.05.004. eCollection 2017 Aug. PubMed PMID: 28560278; PubMed Central PMCID: PMC5440284.

11: Rovira AR, Fin A, Tor Y. Expanding a fluorescent RNA alphabet: synthesis, photophysics and utility of isothiazole-derived purine nucleoside surrogates. Chem Sci. 2017 Apr 1;8(4):2983-2993. doi: 10.1039/c6sc05354h. Epub 2017 Jan 30. PubMed PMID: 28451365; PubMed Central PMCID: PMC5380116.

12: Tsotsoros SD, Lutz PB, Daniel AG, Peterson EJ, de Paiva REF, Rivera E, Qu Y, Bayse CA, Farrell NP. Enhancement of the physicochemical properties of [Pt(dien)(nucleobase)](2+) for HIVNCp7 targeting. Chem Sci. 2017 Feb 1;8(2):1269-1281. doi: 10.1039/c6sc03445d. Epub 2016 Oct 6. PubMed PMID: 28451269; PubMed Central PMCID: PMC5369524.

13: Law KP, Han TL, Mao X, Zhang H. Tryptophan and purine metabolites are consistently upregulated in the urinary metabolome of patients diagnosed with gestational diabetes mellitus throughout pregnancy: A longitudinal metabolomics study of Chinese pregnant women part 2. Clin Chim Acta. 2017 May;468:126-139. doi: 10.1016/j.cca.2017.02.018. Epub 2017 Feb 24. PubMed PMID: 28238935.

14: Ashihara H, Mizuno K, Yokota T, Crozier A. Xanthine Alkaloids: Occurrence, Biosynthesis, and Function in Plants. Prog Chem Org Nat Prod. 2017;105:1-88. doi: 10.1007/978-3-319-49712-9_1. Review. PubMed PMID: 28194561.

15: Beringer A, Citterio-Quentin A, Otero RO, Gustin C, Clarke R, Salvi JP, Boulieu R. Determination of inosine 5'-monophosphate dehydrogenase activity in red blood cells of thiopurine-treated patients using HPLC. J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Feb 15;1044-1045:194-199. doi: 10.1016/j.jchromb.2017.01.006. Epub 2017 Jan 10. PubMed PMID: 28110955.

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