WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 598015
Description: WWamide-2 is a neuromodulatory peptide from the ganglia of African giant snail, Achatina fulica.
MedKoo Cat#: 598015
Chemical Formula: C46H65N13O10S
Exact Mass: 991.4698
Molecular Weight: 992.16
Elemental Analysis: C, 55.69; H, 6.60; N, 18.35; O, 16.13; S, 3.23
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Synonym: WWamide-2; H-Trp-arg-glu-met-ser-val-trp-NH2;
IUPAC/Chemical Name: (2S,5S,8S,11S,14S)-2-((1H-indol-3-yl)methyl)-1-amino-14-((S)-2-((S)-2-amino-3-(1H-indol-3-yl)propanamido)-5-guanidinopentanamido)-8-(hydroxymethyl)-5-isopropyl-11-(2-(methylthio)ethyl)-1,4,7,10,13-pentaoxo-3,6,9,12-tetraazaheptadecan-17-oic acid
InChi Key: RMNKMKCOIFCEDB-HBZGSTDOSA-N
InChi Code: InChI=1S/C46H65N13O10S/c1-24(2)38(45(69)57-35(39(48)63)20-26-22-53-31-12-7-5-10-28(26)31)59-44(68)36(23-60)58-43(67)34(16-18-70-3)56-42(66)33(14-15-37(61)62)55-41(65)32(13-8-17-51-46(49)50)54-40(64)29(47)19-25-21-52-30-11-6-4-9-27(25)30/h4-7,9-12,21-22,24,29,32-36,38,52-53,60H,8,13-20,23,47H2,1-3H3,(H2,48,63)(H,54,64)(H,55,65)(H,56,66)(H,57,69)(H,58,67)(H,59,68)(H,61,62)(H4,49,50,51)/t29-,32-,33-,34-,35-,36-,38-/m0/s1
SMILES Code: O=C(N)[C@H](CC1=CNC2=C1C=CC=C2)NC([C@H](C(C)C)NC([C@H](CO)NC([C@H](CCSC)NC([C@H](CCC(O)=O)NC([C@H](CCCNC(N)=N)NC([C@H](CC3=CNC4=C3C=CC=C4)N)=O)=O)=O)=O)=O)=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.03.00
The following data is based on the product molecular weight 992.16 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Minakata H, Ikeda T, Muneoka Y, Kobayashi M, Nomoto K. WWamide-1, -2 and -3: novel neuromodulatory peptides isolated from ganglia of the African giant snail, Achatina fulica. FEBS Lett. 1993 May 24;323(1-2):104-8. PubMed PMID: 8495720.