N-Valyltryptophan

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 598001

CAS#: 24587-37-9

Description: N-Valyltryptophan is a dipeptide composed of valine and tryptophan. It is an incomplete breakdown product of protein digestion or protein catabolism. Some dipeptides are known to have physiological or cell-signaling effects although most are simply short-lived intermediates on their way to specific amino acid degradation pathways following further proteolysis.


Price and Availability

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N-Valyltryptophan is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 598001
Name: N-Valyltryptophan
CAS#: 24587-37-9
Chemical Formula: C16H21N3O3
Exact Mass: 303.1583
Molecular Weight: 303.36
Elemental Analysis: C, 63.35; H, 6.98; N, 13.85; O, 15.82


Synonym: N-Valyltryptophan; Val-trp; L-Valyl-L-tryptophan;

IUPAC/Chemical Name: L-valyl-L-tryptophan

InChi Key: LZDNBBYBDGBADK-KBPBESRZSA-N

InChi Code: InChI=1S/C16H21N3O3/c1-9(2)14(17)15(20)19-13(16(21)22)7-10-8-18-12-6-4-3-5-11(10)12/h3-6,8-9,13-14,18H,7,17H2,1-2H3,(H,19,20)(H,21,22)/t13-,14-/m0/s1

SMILES Code: O=C(O)[C@H](CC1=CNC2=C1C=CC=C2)NC([C@H](C(C)C)N)=O


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
2934.99.03.00


References

1: Li Y, Wang F, Zhang PZ, Yang M. [Chemical Constituents from Periplaneta americana]. Zhong Yao Cai. 2015 Oct;38(10):2038-41. Chinese. PubMed PMID: 27254913.

2: Lunow D, Kaiser S, Rückriemen J, Pohl C, Henle T. Tryptophan-containing dipeptides are C-domain selective inhibitors of angiotensin converting enzyme. Food Chem. 2015 Jan 1;166:596-602. doi: 10.1016/j.foodchem.2014.06.059. Epub 2014 Jun 18. PubMed PMID: 25053098.

3: Boudesocque L, Kapel R, Paris C, Dhulster P, Marc I, Renault JH. Concentration and selective fractionation of an antihypertensive peptide from an alfalfa white proteins hydrolysate by mixed ion-exchange centrifugal partition chromatography. J Chromatogr B Analyt Technol Biomed Life Sci. 2012 Sep 15;905:23-30. doi: 10.1016/j.jchromb.2012.07.034. Epub 2012 Aug 3. PubMed PMID: 22939269.

4: Hatanaka A, Miyahara H, Suzuki KI, Sato S. Isolation and identification of antihypertensive peptides from antarctic krill tail meat hydrolysate. J Food Sci. 2009 May-Jul;74(4):H116-20. doi: 10.1111/j.1750-3841.2009.01138.x. PubMed PMID: 19490329.

5: Holden HM, Matthews BW. The binding of L-valyl-L-tryptophan to crystalline thermolysin illustrates the mode of interaction of a product of peptide hydrolysis. J Biol Chem. 1988 Mar 5;263(7):3256-60. PubMed PMID: 3343246.