N-Valyltryptophan

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 598001

CAS#: 24587-37-9

Description: N-Valyltryptophan is a dipeptide composed of valine and tryptophan. It is an incomplete breakdown product of protein digestion or protein catabolism. Some dipeptides are known to have physiological or cell-signaling effects although most are simply short-lived intermediates on their way to specific amino acid degradation pathways following further proteolysis.


Chemical Structure

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N-Valyltryptophan
CAS# 24587-37-9

Theoretical Analysis

MedKoo Cat#: 598001
Name: N-Valyltryptophan
CAS#: 24587-37-9
Chemical Formula: C16H21N3O3
Exact Mass: 303.1583
Molecular Weight: 303.36
Elemental Analysis: C, 63.35; H, 6.98; N, 13.85; O, 15.82

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: N-Valyltryptophan; Val-trp; L-Valyl-L-tryptophan;

IUPAC/Chemical Name: L-valyl-L-tryptophan

InChi Key: LZDNBBYBDGBADK-KBPBESRZSA-N

InChi Code: InChI=1S/C16H21N3O3/c1-9(2)14(17)15(20)19-13(16(21)22)7-10-8-18-12-6-4-3-5-11(10)12/h3-6,8-9,13-14,18H,7,17H2,1-2H3,(H,19,20)(H,21,22)/t13-,14-/m0/s1

SMILES Code: O=C(O)[C@H](CC1=CNC2=C1C=CC=C2)NC([C@H](C(C)C)N)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

Preparing Stock Solutions

The following data is based on the product molecular weight 303.36 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Li Y, Wang F, Zhang PZ, Yang M. [Chemical Constituents from Periplaneta americana]. Zhong Yao Cai. 2015 Oct;38(10):2038-41. Chinese. PubMed PMID: 27254913.

2: Lunow D, Kaiser S, Rückriemen J, Pohl C, Henle T. Tryptophan-containing dipeptides are C-domain selective inhibitors of angiotensin converting enzyme. Food Chem. 2015 Jan 1;166:596-602. doi: 10.1016/j.foodchem.2014.06.059. Epub 2014 Jun 18. PubMed PMID: 25053098.

3: Boudesocque L, Kapel R, Paris C, Dhulster P, Marc I, Renault JH. Concentration and selective fractionation of an antihypertensive peptide from an alfalfa white proteins hydrolysate by mixed ion-exchange centrifugal partition chromatography. J Chromatogr B Analyt Technol Biomed Life Sci. 2012 Sep 15;905:23-30. doi: 10.1016/j.jchromb.2012.07.034. Epub 2012 Aug 3. PubMed PMID: 22939269.

4: Hatanaka A, Miyahara H, Suzuki KI, Sato S. Isolation and identification of antihypertensive peptides from antarctic krill tail meat hydrolysate. J Food Sci. 2009 May-Jul;74(4):H116-20. doi: 10.1111/j.1750-3841.2009.01138.x. PubMed PMID: 19490329.

5: Holden HM, Matthews BW. The binding of L-valyl-L-tryptophan to crystalline thermolysin illustrates the mode of interaction of a product of peptide hydrolysis. J Biol Chem. 1988 Mar 5;263(7):3256-60. PubMed PMID: 3343246.