U-34728E (HCl)

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MedKoo CAT#: 597951

CAS#: 58801-45-9

Description: U-34728E (HCl) is a bioactive chemical.


Price and Availability

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Pricing updated 2020-09-28. Prices are subject to change without notice.

U-34728E (HCl) is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 597951
Name: U-34728E (HCl)
CAS#: 58801-45-9
Chemical Formula: C19H37Cl3N2O6S
Exact Mass:
Molecular Weight: 527.92
Elemental Analysis: C, 43.23; H, 7.06; Cl, 20.14; N, 5.31; O, 18.18; S, 6.07


Related CAS #: 40984-87-0 (free base)    

Synonym: U-34728E (HCl); U34728E (HCl); U 34728E (HCl);

IUPAC/Chemical Name: (2S,4R)-N-((1S,2S)-2-chloro-1-((2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(methylthio)tetrahydro-2H-pyran-2-yl)propyl)-1-(2-hydroxyethyl)-4-propylpyrrolidine-2-carboxamide dihydrochloride

InChi Key: KPMIWBUMRJQKIZ-GFNAYIDLSA-N

InChi Code: InChI=1S/C19H35ClN2O6S.2ClH/c1-4-5-11-8-12(22(9-11)6-7-23)18(27)21-13(10(2)20)17-15(25)14(24)16(26)19(28-17)29-3;;/h10-17,19,23-26H,4-9H2,1-3H3,(H,21,27);2*1H/t10-,11+,12-,13+,14-,15+,16+,17+,19+;;/m0../s1

SMILES Code: CCC[C@@H]1C[C@@H](C(N[C@@H]([C@H]2O[C@@H]([C@@H]([C@H]([C@H]2O)O)O)SC)[C@@H](Cl)C)=O)N(C1)CCO.Cl.Cl


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.03.00


References

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9: Foroutan-Nejad C, Vícha J, Marek R, Patzschke M, Straka M. Unwilling U-U bonding in U2@C80: cage-driven metal-metal bonds in di-uranium fullerenes. Phys Chem Chem Phys. 2015 Oct 7;17(37):24182-92. doi: 10.1039/c5cp04280a. Epub 2015 Sep 1. PubMed PMID: 26325667.

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11: Eby EL, Zagar AJ, Wang P, Curtis BH, Xie J, Haldane DC, Idris I, Peters AL, Hood RC, Jackson JA. Healthcare costs and adherence associated with human regular U-500 versus high-dose U-100 insulin in patients with diabetes. Endocr Pract. 2014 Jul;20(7):663-70. doi: 10.4158/EP13407.OR. PubMed PMID: 24449672.

12: Tsompos C, Panoulis C, Toutouzas K, Zografos G, Papalois A. The Effect of the Antioxidant Drug "U-74389G" on Creatinine Levels during Ischemia Reperfusion Injury in Rats. Curr Urol. 2016 May;9(2):73-8. doi: 10.1159/000442857. Epub 2016 May 20. PubMed PMID: 27390579; PubMed Central PMCID: PMC4911526.

13: Peyrard T, Lam Y, Saison C, Arnaud L, Babinet J, Rouger P, Bierling P, Janvier D. Anti-U-like as an alloantibody in S-s-U- and S-s-U+(var) black people. Transfusion. 2012 Mar;52(3):622-8. doi: 10.1111/j.1537-2995.2011.03318.x. Epub 2011 Aug 31. PubMed PMID: 21880045.

14: Lam OP, Franke SM, Heinemann FW, Meyer K. Reactivity of U-E-U (E = S, Se) toward CO2, CS2, and COS: new mixed-carbonate complexes of the types U-CO2E-U (E = S, Se), U-CS2E-U (E = O, Se), and U-COSSe-U. J Am Chem Soc. 2012 Oct 10;134(40):16877-81. doi: 10.1021/ja307539w. Epub 2012 Sep 28. PubMed PMID: 22970905.

15: Mathers C, Spencer CM, Munger J. Distinct domains within the human cytomegalovirus U(L)26 protein are important for wildtype viral replication and virion stability. PLoS One. 2014 Feb 5;9(2):e88101. doi: 10.1371/journal.pone.0088101. eCollection 2014. Erratum in: PLoS One. 2014;9(12):e114927. PubMed PMID: 24505393; PubMed Central PMCID: PMC3914908.

16: Yang Y, Zhang P. First-principles molecular dynamics study of water dissociation on the γ-U(1 0 0) surface. J Phys Condens Matter. 2015 May 8;27(17):175005. doi: 10.1088/0953-8984/27/17/175005. Epub 2015 Apr 2. PubMed PMID: 25835568.

17: Jemison NE, Johnson TM, Shiel AE, Lundstrom CC. Uranium Isotopic Fractionation Induced by U(VI) Adsorption onto Common Aquifer Minerals. Environ Sci Technol. 2016 Nov 15;50(22):12232-12240. Epub 2016 Oct 28. PubMed PMID: 27758097.

18: Harrison JJ, Payne TE, Wilsher KL, Thiruvoth S, Child DP, Johansen MP, Hotchkis MA. Measurement of (233)U/(234)U ratios in contaminated groundwater using alpha spectrometry. J Environ Radioact. 2016 Jan;151 Pt 3:537-41. doi: 10.1016/j.jenvrad.2015.08.013. Epub 2015 Sep 7. PubMed PMID: 26359847.

19: Lowson RT. (234)U/(238)U signatures associated with uranium ore bodies: part 3 Koongarra. J Environ Radioact. 2013 Apr;118:163-8. doi: 10.1016/j.jenvrad.2012.10.004. Epub 2012 Nov 8. PubMed PMID: 23142336.

20: Mougel V, Pécaut J, Mazzanti M. New polynuclear U(IV)-U(V) complexes from U(IV) mediated uranyl(V) disproportionation. Chem Commun (Camb). 2012 Jan 21;48(6):868-70. doi: 10.1039/c1cc16646h. Epub 2011 Dec 1. PubMed PMID: 22134746.