NSC-84096

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 558419

CAS#: 908813-78-5

Description: NSC-84096 is an inhibitor of endopeptidase activity of botulinum neurotoxin type A light chain (rBoNT/A-LC).


Chemical Structure

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NSC-84096
CAS# 908813-78-5

Theoretical Analysis

MedKoo Cat#: 558419
Name: NSC-84096
CAS#: 908813-78-5
Chemical Formula: C25H19N3O
Exact Mass: 377.15
Molecular Weight: 377.450
Elemental Analysis: C, 79.55; H, 5.07; N, 11.13; O, 4.24

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: NSC-84096; NSC 84096; NSC84096; CID-256758; CID 256758; CID256758;

IUPAC/Chemical Name: 7-[phenyl-(quinolin-8-ylamino)methyl]quinolin-8-ol

InChi Key: RBSPENDGIMQZGB-UHFFFAOYSA-N

InChi Code: InChI=1S/C25H19N3O/c29-25-20(14-13-19-11-6-16-27-24(19)25)22(17-7-2-1-3-8-17)28-21-12-4-9-18-10-5-15-26-23(18)21/h1-16,22,28-29H

SMILES Code: OC1=C2N=CC=CC2=CC=C1C(C3=CC=CC=C3)NC4=C5N=CC=CC5=CC=C4

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 377.45 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Singh P, Singh MK, Chaudhary D, Chauhan V, Bharadwaj P, Pandey A, Upadhyay N, Dhaked RK. Small-molecule quinolinol inhibitor identified provides protection against BoNT/A in mice. PLoS One. 2012;7(10):e47110. doi: 10.1371/journal.pone.0047110. Epub 2012 Oct 11. Retraction in: PLoS One.
2013;8(9). doi: 10.1371/annotation/049f74d0-919f-483c-a488-4740ec0a5f4d. PubMed PMID: 23071727; PubMed Central PMCID: PMC3469547.