WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 597786
Description: Ige decapeptide is a peptide.
MedKoo Cat#: 597786
Name: Ige decapeptide
Chemical Formula: C55H80N12O13
Exact Mass: 1116.5968
Molecular Weight: 1117.31
Elemental Analysis: C, 59.12; H, 7.22; N, 15.04; O, 18.61
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.
Synonym: Ige decapeptide; Immunoglobulin E decapeptide;
IUPAC/Chemical Name: L-lysyl-L-threonyl-L-lysylglycyl-L-serylglycyl-L-phenylalanyl-L-phenylalanyl-L-valyl-L-phenylalanine
InChi Key: LBWHYNPDTSNGQD-NSHCULHESA-N
InChi Code: InChI=1S/C55H80N12O13/c1-33(2)46(53(77)65-42(55(79)80)29-37-21-11-6-12-22-37)66-52(76)41(28-36-19-9-5-10-20-36)64-51(75)40(27-35-17-7-4-8-18-35)61-44(70)30-60-50(74)43(32-68)62-45(71)31-59-49(73)39(24-14-16-26-57)63-54(78)47(34(3)69)67-48(72)38(58)23-13-15-25-56/h4-12,17-22,33-34,38-43,46-47,68-69H,13-16,23-32,56-58H2,1-3H3,(H,59,73)(H,60,74)(H,61,70)(H,62,71)(H,63,78)(H,64,75)(H,65,77)(H,66,76)(H,67,72)(H,79,80)/t34-,38+,39+,40+,41+,42+,43+,46+,47+/m1/s1
SMILES Code: O=C(O)[C@H](CC1=CC=CC=C1)NC([C@H](C(C)C)NC([C@H](CC2=CC=CC=C2)NC([C@H](CC3=CC=CC=C3)NC(CNC([C@H](CO)NC(CNC([C@H](CCCCN)NC([C@H]([C@H](O)C)NC([C@H](CCCCN)N)=O)=O)=O)=O)=O)=O)=O)=O)=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.03.00
The following data is based on the product molecular weight 1117.31 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Drake-Lee A, Jones V, Lewin I, Nayyar S, Wells A, Stanworth D. Levels of substance P and IgE decapeptide in nasal polyp fluid and matching sera: a preliminary study. J Laryngol Otol. 1996 Mar;110(3):225-7. PubMed PMID: 8730355.
2: Stanworth DR, Coleman JW, Khan Z. Essential structural requirements for triggering of mast cells by a synthetic peptide comprising a sequence in the C epsilon 4 domain of human IgE. Mol Immunol. 1984 Mar;21(3):243-7. PubMed PMID: 6425646.
3: Coleman JW, Holgate ST, Church MK, Godfrey RC. Immunoglobulin E decapeptide-induced 5-hydroxytryptamine release from rat peritoneal mast cells. Comparison with corticotropin-(1-24)-peptide, polyarginine, polylysine and antigen. Biochem J. 1981 Sep 15;198(3):615-9. PubMed PMID: 7326027; PubMed Central PMCID: PMC1163309.
4: Burt DS, Stanworth DR. Changes in cellular levels of cyclic AMP in rat mast cells during secretion of histamine induced by immunoglobulin E decapeptide and ACTH(1-24) peptide. Comparison with immunological and ionophore triggers. Biochim Biophys Acta. 1983 Jun 2;762(3):458-65. PubMed PMID: 6189527.