WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 592152
CAS#: 60045-88-7
Description: Fagaramide has Antiplasmodial activity.
MedKoo Cat#: 592152
Name: Fagaramide
CAS#: 60045-88-7
Chemical Formula: C14H17NO3
Exact Mass: 247.1208
Molecular Weight: 247.29
Elemental Analysis: C, 68.00; H, 6.93; N, 5.66; O, 19.41
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.
Synonym: Fagaramide; AI3-30755; AI3 30755; AI330755
IUPAC/Chemical Name: 2-Propenamide, 3-(1,3-benzodioxol-5-yl)-N-(2-methylpropyl)-
InChi Key: WKWYNAMJWDRHBP-GQCTYLIASA-N
InChi Code: InChI=1S/C14H17NO3/c1-10(2)8-15-14(16)6-4-11-3-5-12-13(7-11)18-9-17-12/h3-7,10H,8-9H2,1-2H3,(H,15,16)/b6-4+
SMILES Code: O=C(NCC(C)C)/C=C/C1=CC=C(OCO2)C2=C1
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.03.00
The following data is based on the product molecular weight 247.29 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
1: Adia MM, Emami SN, Byamukama R, Faye I, Borg-Karlson AK. Antiplasmodial activity and phytochemical analysis of extracts from selected Ugandan medicinal plants. J Ethnopharmacol. 2016 Jun 20;186:14-19. doi: 10.1016/j.jep.2016.03.047. Epub 2016 Mar 24. PubMed PMID: 27019273.
2: Anyanwu GO, Nisar-ur-Rehman, Onyeneke CE, Rauf K. Medicinal plants of the genus Anthocleista--A review of their ethnobotany, phytochemistry and pharmacology. J Ethnopharmacol. 2015 Dec 4;175:648-67. doi: 10.1016/j.jep.2015.09.032. Epub 2015 Nov 11. Review. PubMed PMID: 26432351.
3: Neal JJ. Myristicin, safrole, and fagaramide as phytosynergists of xanthotoxin. J Chem Ecol. 1989 Jan;15(1):309-15. doi: 10.1007/BF02027792. PubMed PMID: 24271445.
4: Ayofor JF, Ngadjui BT, Sondengam BL, Tsamo E. A Contribution to the Phytochemistry of Zanthoxylum tessmannii1. Planta Med. 1984 Jun;50(3):210-2. PubMed PMID: 17340299.
5: Moody JO, Sofowora A. Leaf Alkaloids of Zanthoxylum rubescens. Planta Med. 1984 Feb;50(1):101-3. PubMed PMID: 17340264.
6: Oriowo MA. Anti-inflammatory activity of piperonyl-4-acrylic isobutyl amide, an extractive from Zanthoxylum zanthoxyloides. Planta Med. 1982 Jan;44(1):54-6. PubMed PMID: 7063561.
7: Essien EM, Okogun JI. Effect of the root extract of Fagara zanthoxyloides on blood coagulation. Thromb Haemost. 1976 Dec 31;36(3):525-31. PubMed PMID: 1037149.