U 67827E

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MedKoo CAT#: 597740

CAS#: 103494-23-1

Description: U 67827E is a long-lasting cholecystokinin agonist U 67827E decreases food intake.

Price and Availability

Size Price Shipping out time Quantity
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Pricing updated 2020-09-28. Prices are subject to change without notice.

U 67827E is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 597740
Name: U 67827E
CAS#: 103494-23-1
Chemical Formula: C53H68N10O17S
Exact Mass: 1148.4485
Molecular Weight: 1149.24
Elemental Analysis: C, 55.39; H, 5.96; N, 12.19; O, 23.67; S, 2.79

Synonym: U 67827E; U-67827E; U67827E; N-Ac-Asp-tyr(So3H)-nle-gly-trp-nle-asp-phe-NH2;

IUPAC/Chemical Name: (3S,6S,9S,15S,18S,21S)-9-((1H-indol-3-yl)methyl)-19-acetyl-21-amino-3-(((S)-1-amino-1-oxo-3-phenylpropan-2-yl)carbamoyl)-6,15-dibutyl-5,8,11,14,17,20-hexaoxo-18-(4-(sulfooxy)benzyl)-4,7,10,13,16,19-hexaazatricosanedioic acid


InChi Code: InChI=1S/C53H68N10O17S/c1-4-6-16-38(60-52(75)43(63(30(3)64)53(76)36(54)26-45(66)67)24-32-19-21-34(22-20-32)80-81(77,78)79)48(71)57-29-44(65)58-41(25-33-28-56-37-18-12-11-15-35(33)37)50(73)59-39(17-7-5-2)49(72)62-42(27-46(68)69)51(74)61-40(47(55)70)23-31-13-9-8-10-14-31/h8-15,18-22,28,36,38-43,56H,4-7,16-17,23-27,29,54H2,1-3H3,(H2,55,70)(H,57,71)(H,58,65)(H,59,73)(H,60,75)(H,61,74)(H,62,72)(H,66,67)(H,68,69)(H,77,78,79)/t36-,38-,39-,40-,41-,42-,43-/m0/s1

SMILES Code: O=C(N)[C@H](CC1=CC=CC=C1)NC([C@H](CC(O)=O)NC([C@H](CCCC)NC([C@H](CC2=CNC3=C2C=CC=C3)NC(CNC([C@H](CCCC)NC([C@H](CC4=CC=C(OS(=O)(O)=O)C=C4)N(C([C@H](CC(O)=O)N)=O)C(C)=O)=O)=O)=O)=O)=O)=O

Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1: Moran TH, Sawyer TK, Seeb DH, Ameglio PJ, Lombard MA, McHugh PR. Potent and sustained satiety actions of a cholecystokinin octapeptide analogue. Am J Clin Nutr. 1992 Jan;55(1 Suppl):286S-290S. doi: 10.1093/ajcn/55.1.286s. PubMed PMID: 1728841.

2: Foltin RW, Moran TH. Food intake in baboons: effects of a long-acting cholecystokinin analog. Appetite. 1989 Apr;12(2):145-52. PubMed PMID: 2764555.

3: Schwartz GJ, Netterville LA, McHugh PR, Moran TH. Gastric loads potentiate inhibition of food intake produced by a cholecystokinin analogue. Am J Physiol. 1991 Nov;261(5 Pt 2):R1141-6. PubMed PMID: 1951762.