L 363564

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 559186

CAS#: 86153-46-0

Description: L 363564 is a kidney renin inhibitor.

Chemical Structure

L 363564
CAS# 86153-46-0

Theoretical Analysis

MedKoo Cat#: 559186
Name: L 363564
CAS#: 86153-46-0
Chemical Formula: C54H76N12O10
Exact Mass: 1052.5807
Molecular Weight: 1053.27
Elemental Analysis: C, 61.58; H, 7.27; N, 15.96; O, 15.19

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: L 363564; L-363564; L363564; L-363,564; L 363,564; L363,564; Boc-his-pro-phe-his-statine-leu-phe-NH2;

IUPAC/Chemical Name: tert-butyl (1-(2-((13-((1H-imidazol-5-yl)methyl)-1-amino-2-benzyl-9-hydroxy-5,10-diisobutyl-1,4,7,12,15-pentaoxo-17-phenyl-3,6,11,14-tetraazaheptadecan-16-yl)carbamoyl)pyrrolidin-1-yl)-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl)carbamate


InChi Code: 1S/C54H76N12O10/c1-32(2)21-38(45(67)27-46(68)60-40(22-33(3)4)48(70)62-39(47(55)69)23-34-15-10-8-11-16-34)61-50(72)42(25-36-28-56-30-58-36)63-49(71)41(24-35-17-12-9-13-18-35)64-51(73)44-19-14-20-66(44)52(74)43(26-37-29-57-31-59-37)65-53(75)76-54(5,6)7/h8-13,15-18,28-33,38-45,67H,14,19-27H2,1-7H3,(H2,55,69)(H,56,58)(H,57,59)(H,60,68)(H,61,72)(H,62,70)(H,63,71)(H,64,73)(H,65,75)

SMILES Code: CC(CC(NC(C(NC(C(NC(C1CCCN1C(C(NC(OC(C)(C)C)=O)Cc2[nH]cnc2)=O)=O)Cc3ccccc3)=O)Cc4[nH]cnc4)=O)C(O)CC(NC(C(NC(C(N)=O)Cc5ccccc5)=O)CC(C)C)=O)C

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

Preparing Stock Solutions

The following data is based on the product molecular weight 1053.27 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Foundling SI, Cooper J, Watson FE, Cleasby A, Pearl LH, Sibanda BL, Hemmings A, Wood SP, Blundell TL, Valler MJ, et al. High resolution X-ray analyses of renin inhibitor-aspartic proteinase complexes. Nature. 1987 May 28-Jun 3;327(6120):349-52. PubMed PMID: 3295561.