Neurotensin (1-6)

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MedKoo CAT#: 597554

CAS#: 87620-09-5

Description: Neurotensin (1-6) affects dopamine release from striatum.


Price and Availability

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Pricing updated 2020-10-30. Prices are subject to change without notice.

Neurotensin (1-6) is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 597554
Name: Neurotensin (1-6)
CAS#: 87620-09-5
Chemical Formula: C35H52N8O12
Exact Mass: 776.3705
Molecular Weight: 776.84
Elemental Analysis: C, 54.11; H, 6.75; N, 14.42; O, 24.71


Synonym: Neurotensin (1-6);

IUPAC/Chemical Name: ((S)-5-oxopyrrolidine-2-carbonyl)-L-leucyl-L-tyrosyl-L-glutamyl-L-asparaginyl-L-lysine

InChi Key: FBSIBBLIIBINON-FRSCJGFNSA-N

InChi Code: InChI=1S/C35H52N8O12/c1-18(2)15-24(41-30(49)21-10-12-28(46)38-21)32(51)42-25(16-19-6-8-20(44)9-7-19)33(52)39-22(11-13-29(47)48)31(50)43-26(17-27(37)45)34(53)40-23(35(54)55)5-3-4-14-36/h6-9,18,21-26,44H,3-5,10-17,36H2,1-2H3,(H2,37,45)(H,38,46)(H,39,52)(H,40,53)(H,41,49)(H,42,51)(H,43,50)(H,47,48)(H,54,55)/t21-,22-,23-,24-,25-,26-/m0/s1

SMILES Code: NCCCC[C@@H](C(O)=O)NC([C@H](CC(N)=O)NC([C@H](CCC(O)=O)NC([C@H](CC1=CC=C(O)C=C1)NC([C@H](CC(C)C)NC([C@H](CC2)NC2=O)=O)=O)=O)=O)=O


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.03.00


References

1: Markstein R, Emson P. Effect of neurotensin and its fragments neurotensin-(1-6) and neurotensin-(8-13) on dopamine release from cat striatum. Eur J Pharmacol. 1988 Jul 26;152(1-2):147-52. PubMed PMID: 3208829.

2: Faggin BM, Cubeddu LX. Rapid desensitization of dopamine release induced by neurotensin and neurotensin fragments. J Pharmacol Exp Ther. 1990 May;253(2):812-8. PubMed PMID: 2338657.