N-(Biotin-PEG4)-N-bis(PEG4-acid) HCl salt

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MedKoo CAT#: 572063

CAS#: 2112731-49-2

Description: N-(Biotin-PEG4)-N-bis(PEG4-acid) HCl salt is a PEG Linker. PEG Linkers may be useful in the development of antibody drug conjugates.

Price and Availability

Size Price Shipping out time Quantity
100mg USD 560 Inquiry
250mg USD 1040 Inquiry
500mg USD 1650 Inquiry
Inquire bulk and customized quantity

Pricing updated 2020-02-17. Prices are subject to change without notice.

N-(Biotin-PEG4)-N-bis(PEG4-acid) HCl salt, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 572063
Name: N-(Biotin-PEG4)-N-bis(PEG4-acid) HCl salt
CAS#: 2112731-49-2
Chemical Formula: C42H78N4O18S
Exact Mass: 958.5032
Molecular Weight: 959.16
Elemental Analysis: C, 52.59; H, 8.20; N, 5.84; O, 30.02; S, 3.34

Synonym: N-(Biotin-PEG4)-N-bis(PEG4-acid) HCl salt

IUPAC/Chemical Name: 16-(16-oxo-20-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-3,6,9,12-tetraoxa-15-azaicosyl)-4,7,10,13,19,22,25,28-octaoxa-16-azahentriacontanedioic acid


InChi Code: InChI=1S/C42H78N4O18S/c47-38(4-2-1-3-37-41-36(35-65-37)44-42(52)45-41)43-7-13-55-19-25-61-31-34-64-28-22-58-16-10-46(8-14-56-20-26-62-32-29-59-23-17-53-11-5-39(48)49)9-15-57-21-27-63-33-30-60-24-18-54-12-6-40(50)51/h36-37,41H,1-35H2,(H,43,47)(H,48,49)(H,50,51)(H2,44,45,52)/t36-,37-,41-/m0/s1

SMILES Code: O=C1N[[email protected]@]2([H])CS[[email protected]@H](CCCCC(NCCOCCOCCOCCOCCN(CCOCCOCCOCCOCCC(O)=O)CCOCCOCCOCCOCCC(O)=O)=O)[[email protected]@]2([H])N1

Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:


1: Deng CY, Long YY, Liu S, Chen ZB, Li C. [Construction of biotin-modified polymeric micelles for pancreatic cancer targeted photodynamic therapy]. Yao Xue Xue Bao. 2015 Aug;50(8):1038-44. Chinese. PubMed PMID: 26669006.

2: Zhu W, Song Z, Wei P, Meng N, Teng F, Yang F, Liu N, Feng R. Y-shaped biotin-conjugated poly (ethylene glycol)-poly (epsilon-caprolactone) copolymer for the targeted delivery of curcumin. J Colloid Interface Sci. 2015 Apr 1;443:1-7. doi: 10.1016/j.jcis.2014.11.073. Epub 2014 Dec 6. PubMed PMID: 25526295.

3: Ke S, Wright JC, Kwon GS. Avidin-biotin-PEG-CPA complexes as potential EPR-directed therapeutic protein carriers: preparation and characterization. Bioconjug Chem. 2007 Sep-Oct;18(5):1644-50. Epub 2007 Aug 18. PubMed PMID: 17705554.

4: Kaiser K, Marek M, Haselgrübler T, Schindler H, Gruber HJ. Basic studies on heterobifunctional biotin-PEG conjugates with a 3-(4-pyridyldithio)propionyl marker on the second terminus. Bioconjug Chem. 1997 Jul-Aug;8(4):545-51. PubMed PMID: 9258454.