N-(Biotin)-N-bis(PEG1-alcohol)
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MedKoo CAT#: 572062

CAS#: 2100306-75-8

Description: N-(Biotin)-N-bis(PEG1-alcohol) is a PEG Linker. PEG Linkers may be useful in the development of antibody drug conjugates.


Price and Availability

Size Price Shipping out time Quantity
250mg USD 560 2 Weeks
500mg USD 940 2 Weeks
1g USD 1430 2 Weeks
Inquire bulk and customized quantity

Pricing updated 2020-08-12. Prices are subject to change without notice.

N-(Biotin)-N-bis(PEG1-alcohol), purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 572062
Name: N-(Biotin)-N-bis(PEG1-alcohol)
CAS#: 2100306-75-8
Chemical Formula: C18H33N3O6S
Exact Mass: 419.209
Molecular Weight: 419.54
Elemental Analysis: C, 51.53; H, 7.93; N, 10.02; O, 22.88; S, 7.64


Synonym: N-(Biotin)-N-bis(PEG1-alcohol)

IUPAC/Chemical Name: N,N-bis(2-(2-hydroxyethoxy)ethyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide

InChi Key: NYEUWOGNEWCFCZ-ZOBUZTSGSA-N

InChi Code: InChI=1S/C18H33N3O6S/c22-7-11-26-9-5-21(6-10-27-12-8-23)16(24)4-2-1-3-15-17-14(13-28-15)19-18(25)20-17/h14-15,17,22-23H,1-13H2,(H2,19,20,25)/t14-,15-,17-/m0/s1

SMILES Code: O=C1N[C@@]2([H])CS[C@@H](CCCCC(N(CCOCCO)CCOCCO)=O)[C@@]2([H])N1


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.03.00


References

1: Deng CY, Long YY, Liu S, Chen ZB, Li C. [Construction of biotin-modified polymeric micelles for pancreatic cancer targeted photodynamic therapy]. Yao Xue Xue Bao. 2015 Aug;50(8):1038-44. Chinese. PubMed PMID: 26669006.

2: Zhu W, Song Z, Wei P, Meng N, Teng F, Yang F, Liu N, Feng R. Y-shaped biotin-conjugated poly (ethylene glycol)-poly (epsilon-caprolactone) copolymer for the targeted delivery of curcumin. J Colloid Interface Sci. 2015 Apr 1;443:1-7. doi: 10.1016/j.jcis.2014.11.073. Epub 2014 Dec 6. PubMed PMID: 25526295.

3: Ke S, Wright JC, Kwon GS. Avidin-biotin-PEG-CPA complexes as potential EPR-directed therapeutic protein carriers: preparation and characterization. Bioconjug Chem. 2007 Sep-Oct;18(5):1644-50. Epub 2007 Aug 18. PubMed PMID: 17705554.

4: Kaiser K, Marek M, Haselgrübler T, Schindler H, Gruber HJ. Basic studies on heterobifunctional biotin-PEG conjugates with a 3-(4-pyridyldithio)propionyl marker on the second terminus. Bioconjug Chem. 1997 Jul-Aug;8(4):545-51. PubMed PMID: 9258454.