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MedKoo CAT#: 563208

CAS#: 666256-06-0

Description: NGD9002 is a new generation, topology 2 selective corticotropin releasing factor-1 (CRF-1) receptor antagonist.

Price and Availability

Size Price Shipping out time Quantity
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Pricing updated 2020-10-22. Prices are subject to change without notice.

NGD9002 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to to inquire quote.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 563208
Name: NGD9002
CAS#: 666256-06-0
Chemical Formula: C20H31N5O
Exact Mass: 357.2529
Molecular Weight: 357.5
Elemental Analysis: C, 67.19; H, 8.74; N, 19.59; O, 4.48

Synonym: NGD9002; NGD-9002; NGD 9002;

IUPAC/Chemical Name: 5-(6-Isopropyl-2-methylaminopyridin-3-yl)-[N-(1-ethyl)propyl]-3-methoxy-6-methylpyrazine-2-amine


InChi Code: InChI=1S/C20H31N5O/c1-8-14(9-2)23-19-20(26-7)25-17(13(5)22-19)15-10-11-16(12(3)4)24-18(15)21-6/h10-12,14H,8-9H2,1-7H3,(H,21,24)(H,22,23)


Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1: Million M, Zhao JF, Luckey A, Czimmer J, Maynard GD, Kehne J, Hoffman DC, Taché Y. The newly developed CRF1-receptor antagonists, NGD 98-2 and NGD 9002, suppress acute stress-induced stimulation of colonic motor function and visceral hypersensitivity in rats. PLoS One. 2013 Sep 6;8(9):e73749. doi: 10.1371/journal.pone.0073749. eCollection 2013. PubMed PMID: 24040053; PubMed Central PMCID: PMC3765344.