WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 592027
CAS#: 579-75-9
Description: O-Methylsalicylic acid is a novel antiemetic which prevents nausea and vomiting in humans. Its actions are unclear but most likely involves the chemoreceptor trigger zone (CTZ)
MedKoo Cat#: 592027
Name: O-Methylsalicylic acid
CAS#: 579-75-9
Chemical Formula: C8H8O3
Exact Mass: 152.0473
Molecular Weight: 152.149
Elemental Analysis: C, 63.15; H, 5.30; O, 31.55
Synonym: O-Methylsalicylic acid; NSC 3778; NSC-3778; NSC3778
IUPAC/Chemical Name: Benzoic acid, 2-methoxy-
InChi Key: ILUJQPXNXACGAN-UHFFFAOYSA-N
InChi Code: InChI=1S/C8H8O3/c1-11-7-5-3-2-4-6(7)8(9)10/h2-5H,1H3,(H,9,10)
SMILES Code: O=C(O)C1=CC=CC=C1OC
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.03.00
| Biological target: | O-Methylsalicylic acid is a novel antiemetic which prevents nausea and vomiting in humans. |
| In vitro activity: | TBD |
| In vivo activity: | TBD |
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 65.0 | 427.21 |
The following data is based on the product molecular weight 152.149 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
| Formulation protocol: | TBD |
| In vitro protocol: | TBD |
| In vivo protocol: | TBD |
1: Zhu DX, Zhao JL, Mo L, Li HL. Drug allergy: identification and characterization of IgE-reactivities to aspirin and related compounds. J Investig Allergol Clin Immunol. 1997 May-Jun;7(3):160-8. PubMed PMID: 9252874.
