IDI-3783

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 563175

CAS#: 901031-43-4

Description: IDI-3783 is a mutant-selective Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH) inhibitor.


Chemical Structure

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IDI-3783
CAS# 901031-43-4

Theoretical Analysis

MedKoo Cat#: 563175
Name: IDI-3783
CAS#: 901031-43-4
Chemical Formula: C26H23ClFN3O2S
Exact Mass: 495.1184
Molecular Weight: 495.99
Elemental Analysis: C, 62.96; H, 4.67; Cl, 7.15; F, 3.83; N, 8.47; O, 6.45; S, 6.46

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: IDI-3783; IDI 3783; IDI3783;

IUPAC/Chemical Name: 10-[(2-Chloro-6-fluorophenyl)methyl]-8-[(4-methyl-1-piperazinyl)carbonyl]-dibenzo[b,f][1,4]thiazepin-11(10H)-one

InChi Key: KHTBRACCSUODEU-UHFFFAOYSA-N

InChi Code: InChI=1S/C26H23ClFN3O2S/c1-29-11-13-30(14-12-29)25(32)17-9-10-24-22(15-17)31(16-19-20(27)6-4-7-21(19)28)26(33)18-5-2-3-8-23(18)34-24/h2-10,15H,11-14,16H2,1H3

SMILES Code: O=C1N(CC2=C(F)C=CC=C2Cl)C3=CC(C(N4CCN(C)CC4)=O)=CC=C3SC5=CC=CC=C15

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

Preparing Stock Solutions

The following data is based on the product molecular weight 495.99 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Lukens AK, Ross LS, Heidebrecht R, Javier Gamo F, Lafuente-Monasterio MJ, Booker ML, Hartl DL, Wiegand RC, Wirth DF. Harnessing evolutionary fitness in Plasmodium falciparum for drug discovery and suppressing resistance. Proc Natl Acad Sci U S A. 2014 Jan 14;111(2):799-804. doi: 10.1073/pnas.1320886110. Epub 2013 Dec 31. PubMed PMID: 24381157; PubMed Central PMCID: PMC3896170.