2-Methylanthraquinone
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MedKoo CAT#: 591956

CAS#: 84-54-8

Description: 2-Methylanthraquinone is a component of a Potential Biomarker.


Chemical Structure

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2-Methylanthraquinone
CAS# 84-54-8

Theoretical Analysis

MedKoo Cat#: 591956
Name: 2-Methylanthraquinone
CAS#: 84-54-8
Chemical Formula: C15H10O2
Exact Mass: 222.0681
Molecular Weight: 222.24
Elemental Analysis: C, 81.07; H, 4.54; O, 14.40

Price and Availability

Size Price Availability Quantity
25.0g USD 240.0 2 Weeks
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Synonym: 2-Methylanthraquinone; NSC 607; NSC-607; NSC607

IUPAC/Chemical Name: 2-Methylanthraquinone

InChi Key: NJWGQARXZDRHCD-UHFFFAOYSA-N

InChi Code: InChI=1S/C15H10O2/c1-9-6-7-12-13(8-9)15(17)11-5-3-2-4-10(11)14(12)16/h2-8H,1H3

SMILES Code: O=C(C1=C2C=CC=C1)C3=CC=C(C)C=C3C2=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

Preparing Stock Solutions

The following data is based on the product molecular weight 222.24 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Wang Y, Wang C, Lin H, Liu Y, Li Y, Zhao Y, Li P, Liu J. Discovery of the Potential Biomarkers for Discrimination between Hedyotis diffusa and Hedyotis corymbosa by UPLC-QTOF/MS Metabolome Analysis. Molecules. 2018 Jun 25;23(7). pii: E1525. doi: 10.3390/molecules23071525. PubMed PMID: 29941819.

2: Chen Y, Shan MQ, Wang HL, Xue L, Zhang L, Ding AW. [Changes of chemical constituents in Rubiae Radix et Rhizoma before and after carbonized by UPLC-Q-TOF-MS method]. Zhongguo Zhong Yao Za Zhi. 2017 Mar;42(5):923-930. doi: 10.19540/j.cnki.cjcmm.20170121.035. Chinese. PubMed PMID: 28994536.

3: Ahire V, Das D, Mishra KP, Kulkarni GR, Ackland L. Inhibition of the p53 Y220C Mutant by 1-Hydroxy-2- Methylanthraquinone Derivatives: A Novel Strategy for Cancer Therapy. J Environ Pathol Toxicol Oncol. 2016;35(4):355-364. PubMed PMID: 27992315.

4: Ismayati M, Nakagawa-Izumi A, Kamaluddin NN, Ohi H. Toxicity and Feeding Deterrent Effect of 2-Methylanthraquinone from the Wood Extractives of Tectona grandis on the Subterranean Termites Coptotermes formosanus and Reticulitermes speratus. Insects. 2016 Nov 8;7(4). pii: E63. PubMed PMID: 27834795; PubMed Central PMCID: PMC5198211.

5: Sheng K, Lu J. Typical airborne quinones modulate oxidative stress and cytokine expression in lung epithelial A549 cells. J Environ Sci Health A Tox Hazard Subst Environ Eng. 2017 Jan 28;52(2):127-134. doi: 10.1080/10934529.2016.1237127. Epub 2016 Oct 21. PubMed PMID: 27768525.

6: Dzoyem JP, Donfack AR, Tane P, McGaw LJ, Eloff JN. Inhibition of Nitric Oxide Production in LPS-Stimulated RAW 264.7 Macrophages and 15-LOX Activity by Anthraquinones from Pentas schimperi. Planta Med. 2016 Sep;82(14):1246-51. doi: 10.1055/s-0042-104417. Epub 2016 Apr 19. PubMed PMID: 27093247.

7: Li YL, Zhang J, Min D, Hongyan Z, Lin N, Li QS. Anticancer Effects of 1,3-Dihydroxy-2-Methylanthraquinone and the Ethyl Acetate Fraction of Hedyotis Diffusa Willd against HepG2 Carcinoma Cells Mediated via Apoptosis. PLoS One. 2016 Apr 11;11(4):e0151502. doi: 10.1371/journal.pone.0151502. eCollection 2016. PubMed PMID: 27064569; PubMed Central PMCID: PMC4827846.

8: Verdan MH, Mera de Souza L, Ernesto de Carvalho J, Vendramini Costa DB, Salvador MJ, Barison A, Alves Stefanello MÉ. Two new hydronaphthoquinones from Sinningia aggregata (Gesneriaceae) and cytotoxic activity of aggregatin D. Chem Biodivers. 2015 Jan;12(1):148-52. doi: 10.1002/cbdv.201400281. PubMed PMID: 25641842.

9: Zhu G, Wang Y, Fu H, Xu X, Cui Z, Ji X, Wu G. Photoinduced electron transfer between 2-methylanthraquinone and triethylamine in an ionic liquid: time-resolved EPR and transient absorption spectroscopy study. Spectrochim Acta A Mol Biomol Spectrosc. 2015 Feb 25;137:148-53. doi: 10.1016/j.saa.2014.08.021. Epub 2014 Aug 27. PubMed PMID: 25218223.

10: Chiou CT, Hsu RY, Lin LC. Isolation and cytotoxic effect of anthraquinones from Morinda umbellata. Planta Med. 2014 Aug;80(13):1113-7. doi: 10.1055/s-0034-1382956. Epub 2014 Aug 19. PubMed PMID: 25137574.

11: Wilson MJ, Sabbioni G, Rando R, Miller CA 3rd. Activation of aryl hydrocarbon receptor signaling by extracts of teak and other wood dusts. Environ Toxicol. 2015 Dec;30(12):1375-84. doi: 10.1002/tox.22007. Epub 2014 Jun 5. PubMed PMID: 24898320.

12: Kongyen W, Rukachaisirikul V, Phongpaichit S, Sawangjaroen N, Songsing P, Madardam H. Anthraquinone and naphthoquinone derivatives from the roots of Coptosapelta flavescens. Nat Prod Commun. 2014 Feb;9(2):219-20. PubMed PMID: 24689295.

13: Qiao M, Qi W, Liu H, Qu J. Oxygenated, nitrated, methyl and parent polycyclic aromatic hydrocarbons in rivers of Haihe River System, China: occurrence, possible formation, and source and fate in a water-shortage area. Sci Total Environ. 2014 May 15;481:178-85. doi: 10.1016/j.scitotenv.2014.02.050. Epub 2014 Mar 2. PubMed PMID: 24598148.

14: Shang Y, Zhang L, Jiang Y, Li Y, Lu P. Airborne quinones induce cytotoxicity and DNA damage in human lung epithelial A549 cells: the role of reactive oxygen species. Chemosphere. 2014 Apr;100:42-9. doi: 10.1016/j.chemosphere.2013.12.079. Epub 2014 Jan 27. PubMed PMID: 24480427.

15: Qiao M, Qi W, Liu H, Qu J. Occurrence, behavior and removal of typical substituted and parent polycyclic aromatic hydrocarbons in a biological wastewater treatment plant. Water Res. 2014 Apr 1;52:11-9. doi: 10.1016/j.watres.2013.12.032. Epub 2014 Jan 2. PubMed PMID: 24440761.

16: Zhang D, Chen W, Chen W, Song X, Han C, Wang Y, Chen G. Three new ursane-type triterpenoids from the stems of Saprosma merrillii. Molecules. 2013 Nov 25;18(12):14496-504. doi: 10.3390/molecules181214496. Erratum in: Molecules. 2014;19(11):18618-9. PubMed PMID: 24287986.

17: Akhtar MN, Zareen S, Yeap SK, Ho WY, Lo KM, Hasan A, Alitheen NB. Total synthesis, cytotoxic effects of damnacanthal, nordamnacanthal and related anthraquinone analogues. Molecules. 2013 Aug 20;18(8):10042-55. doi: 10.3390/molecules180810042. PubMed PMID: 23966087.

18: Cao XY, Fu HY, Zhu L, Wu GZ. [Laser photolysis study on photo-oxidation reactions of aromatic amino acids with triplet 2-methylanthraquinone]. Guang Pu Xue Yu Guang Pu Fen Xi. 2013 Apr;33(4):916-20. Chinese. PubMed PMID: 23841398.

19: Chen X, Wang K, Shan MQ, Ding AW. [Simultaneous determination of four quinone compounds in carbonized Rubiae Radix et Rhizoma by UPLC]. Zhongguo Zhong Yao Za Zhi. 2012 Oct;37(19):2922-5. Chinese. PubMed PMID: 23270235.

20: Cysewski P, Jeliński T. Accuracy of color prediction of anthraquinone dyes in methanol solution estimated from first principle quantum chemistry computations. J Mol Model. 2013 Oct;19(10):4089-97. doi: 10.1007/s00894-012-1717-4. Epub 2012 Dec 19. PubMed PMID: 23250806.