Idonic acid

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 597367

CAS#: 1114-17-6

Description: Idonic acid is a stereoisomer of gluconic acid.

Chemical Structure

Idonic acid
CAS# 1114-17-6

Theoretical Analysis

MedKoo Cat#: 597367
Name: Idonic acid
CAS#: 1114-17-6
Chemical Formula: C6H12O7
Exact Mass: 196.0583
Molecular Weight: 196.15
Elemental Analysis: C, 36.74; H, 6.17; O, 57.09

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: Idonic acid; L-Idonate; L-Idonic acid;

IUPAC/Chemical Name: (2R,3S,4R,5S)-2,3,4,5,6-pentahydroxyhexanoic acid


InChi Code: InChI=1S/C6H12O7/c7-1-2(8)3(9)4(10)5(11)6(12)13/h2-5,7-11H,1H2,(H,12,13)/t2-,3+,4-,5+/m0/s1

SMILES Code: OC[C@H](O)[C@@H](O)[C@@H]([C@@H](O)C(O)=O)O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

Preparing Stock Solutions

The following data is based on the product molecular weight 196.15 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.


Dilution Calculator

Calculate the dilution required to prepare a stock solution.

1: Wichelecki DJ, Vendiola JA, Jones AM, Al-Obaidi N, Almo SC, Gerlt JA. Investigating the physiological roles of low-efficiency D-mannonate and D-gluconate dehydratases in the enolase superfamily: pathways for the catabolism of L-gulonate and L-idonate. Biochemistry. 2014 Sep 9;53(35):5692-9. doi: 10.1021/bi500837w. Epub 2014 Aug 27. PubMed PMID: 25145794; PubMed Central PMCID: PMC4159206.

2: Wen YQ, Li JM, Zhang ZZ, Zhang YF, Pan QH. Antibody preparation, gene expression and subcellular localization of L-idonate dehydrogenase in grape berry. Biosci Biotechnol Biochem. 2010;74(12):2413-7. Epub 2010 Dec 7. PubMed PMID: 21150119.

3: DeBolt S, Cook DR, Ford CM. L-tartaric acid synthesis from vitamin C in higher plants. Proc Natl Acad Sci U S A. 2006 Apr 4;103(14):5608-13. Epub 2006 Mar 27. PubMed PMID: 16567629; PubMed Central PMCID: PMC1459401.

4: Bausch C, Ramsey M, Conway T. Transcriptional organization and regulation of the L-idonic acid pathway (GntII system) in Escherichia coli. J Bacteriol. 2004 Mar;186(5):1388-97. PubMed PMID: 14973046; PubMed Central PMCID: PMC344402.

5: Bausch C, Peekhaus N, Utz C, Blais T, Murray E, Lowary T, Conway T. Sequence analysis of the GntII (subsidiary) system for gluconate metabolism reveals a novel pathway for L-idonic acid catabolism in Escherichia coli. J Bacteriol. 1998 Jul;180(14):3704-10. PubMed PMID: 9658018; PubMed Central PMCID: PMC107343.

6: Truesdell SJ, Sims JC, Boerman PA, Seymour JL, Lazarus RA. Pathways for metabolism of ketoaldonic acids in an Erwinia sp. J Bacteriol. 1991 Nov;173(21):6651-6. PubMed PMID: 1938871; PubMed Central PMCID: PMC209011.

7: Boudrant J. Microbial processes for ascorbic acid biosynthesis: a review. Enzyme Microb Technol. 1990 May;12(5):322-9. Review. PubMed PMID: 1366548.

8: Freeman C, Hopwood JJ. Sanfilippo D syndrome: estimation of N-acetylglucosamine-6-sulfatase activity with a radiolabeled monosulfated disaccharide substrate. Anal Biochem. 1989 Feb 1;176(2):244-8. PubMed PMID: 2500866.

9: Saito K, Kasai Z. Synthesis of l-(+)-Tartaric Acid from l-Ascorbic Acid via 5-Keto-d-Gluconic Acid in Grapes. Plant Physiol. 1984 Sep;76(1):170-4. PubMed PMID: 16663792; PubMed Central PMCID: PMC1064250.

10: Mahuran D, Clements P, Hopwood J. A rapid four column purification of 2-deoxy-D-glucoside-2-sulphamate sulphohydrolase from human liver. Biochim Biophys Acta. 1983 Jun 9;757(3):359-65. PubMed PMID: 6849981.

11: Hopwood JJ, Elliott H. Diagnosis of Sanfilippo type A syndrome by estimation of sulfamidase activity using a radiolabelled tetrasaccharide substrate. Clin Chim Acta. 1982 Aug 18;123(3):241-50. PubMed PMID: 6811162.

12: Hopwood JJ, Elliott H. Detection of the Sanfilippo type B syndrome using radiolabelled oligosaccharides as substrates for the estimation of alpha-N-acetylglucosaminidase. Clin Chim Acta. 1982 Mar 26;120(1):77-86. PubMed PMID: 6802523.

13: Hopwood JJ, Elliott H. Sulphamidase activity in leucocytes, cultured skin fibroblasts and amniotic cells: diagnosis of the Sanfilippo A syndrome with the use of radiolabelled disaccharide substrate. Clin Sci (Lond). 1981 Dec;61(6):729-35. PubMed PMID: 6794973.

14: Hopwood JJ, Elliott H. Radiolabelled oligosaccharides as substrates for the estimation of sulfamidase and the detection of the Sanfilippo type A syndrome. Clin Chim Acta. 1981 Apr 27;112(1):55-66. PubMed PMID: 6786803.

15: Makover S, Ramsey GB, Vane FM, Witt CG, Wright RB. New mechanisms for the biosynthesis and metabolism of 2-keto-L-gulonic acid in bacteria. Biotechnol Bioeng. 1975 Oct;17(10):1485-1514. PubMed PMID: 1182275.

16: MIKI T, HASEGAWA T, SAHASHI Y. Studies on 5-keto-D-gluconate obtained by fermentation relating to L-ascorbic acid. I. Catalytic reduction of 5-keto-D-gluconate to L-idonate. J Vitaminol (Kyoto). 1960 Sep 10;6:205-10. PubMed PMID: 13770520.