WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 597353
CAS#: 62835-71-6
Description: Prolyldiketopiperazine B is a proline-based diketopiperazine.
MedKoo Cat#: 597353
Name: Prolyldiketopiperazine B
CAS#: 62835-71-6
Chemical Formula: C12H20N2O2
Exact Mass: 224.1525
Molecular Weight: 224.3
Elemental Analysis: C, 64.26; H, 8.99; N, 12.49; O, 14.27
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
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Synonym: Prolyldiketopiperazine B; L-Homoleucyl-D-proline lactam; Homoleucyl-D-proline lactam, L-;
IUPAC/Chemical Name: (3S,8aR)-3-isopentylhexahydropyrrolo[1,2-a]pyrazine-1,4-dione
InChi Key: IGZIEGLOLSUNTO-VHSXEESVSA-N
InChi Code: InChI=1S/C12H20N2O2/c1-8(2)5-6-9-12(16)14-7-3-4-10(14)11(15)13-9/h8-10H,3-7H2,1-2H3,(H,13,15)/t9-,10+/m0/s1
SMILES Code: O=C(N[C@H]1CCC(C)C)[C@](CCC2)([H])N2C1=O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.03.00
The following data is based on the product molecular weight 224.3 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
1: Macherla VR, Liu J, Bellows C, Teisan S, Nicholson B, Lam KS, Potts BC. Glaciapyrroles A, B, and C, pyrrolosesquiterpenes from a Streptomyces sp. isolated from an Alaskan marine sediment. J Nat Prod. 2005 May;68(5):780-3. PubMed PMID: 15921430.
2: Houston DR, Synstad B, Eijsink VG, Stark MJ, Eggleston IM, van Aalten DM. Structure-based exploration of cyclic dipeptide chitinase inhibitors. J Med Chem. 2004 Nov 4;47(23):5713-20. PubMed PMID: 15509170.
3: Smith GD, Zabrocki J, Flak TA, Marshall GR. Conformational mimicry. II. An obligatory cis amide bond in a small linear peptide. Int J Pept Protein Res. 1991 Mar;37(3):191-7. PubMed PMID: 1869370.
