U 77436

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MedKoo CAT#: 597320

CAS#: 128657-36-3

Description: U 77436 is a renin inhibitory peptide.

Price and Availability

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Pricing updated 2020-09-23. Prices are subject to change without notice.

U 77436 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 597320
Name: U 77436
CAS#: 128657-36-3
Chemical Formula: C50H76N10O11
Exact Mass: 992.5695
Molecular Weight: 993.21
Elemental Analysis: C, 60.47; H, 7.71; N, 14.10; O, 17.72

Synonym: U 77436; U-77436; U77436;

IUPAC/Chemical Name: L-Histidinamide, 1-(((2-hydroxy-1,1-bis(hydroxymethyl)ethyl)amino)carbonyl)-L-prolyl-L-phenylalanyl-N-(2-hydroxy-5-methyl-1-(2-methylpropyl)-4-(((2-methyl-1-(((2-pyridinylmethyl)amino)carbonyl)butyl)amino)carbonyl)hexyl)-Nalpha-methyl-, N-oxide, (1R-(1R*,2R*,4R*(1R*,2R*)))-


InChi Code: InChI=1S/C50H76N10O11/c1-8-33(6)43(46(67)53-26-35-17-12-13-19-52-35)56-44(65)37(32(4)5)24-42(64)40(21-31(2)3)58(7)41(23-36-25-51-30-54-36)48(69)60(71)47(68)38(22-34-15-10-9-11-16-34)55-45(66)39-18-14-20-59(39)49(70)57-50(27-61,28-62)29-63/h9-13,15-17,19,25,30-33,37-43,60-64H,8,14,18,20-24,26-29H2,1-7H3,(H,51,54)(H,53,67)(H,55,66)(H,56,65)(H,57,70)/t33?,37-,38+,39+,40-,41+,42-,43?/m1/s1

SMILES Code: O=C([NH+]([O-])C([C@H](CC1=CC=CC=C1)NC([C@H]2N(C(NC(CO)(CO)CO)=O)CCC2)=O)=O)[C@H](CC3=CNC=N3)N([C@H](CC(C)C)[C@H](O)C[C@@H](C(NC(C(NCC4=NC=CC=C4)=O)C(C)CC)=O)C(C)C)C

Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO

Shelf Life:
>3 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:


1: Sheehy AM, Hoover JL, Rush BD, Wilkinson KF, Vidmar TJ, Ruwart MJ. Intrapulmonary delivery of renin inhibitory peptides results in sustained release because of saturable transport. Pharm Res. 1993 Oct;10(10):1548-51. PubMed PMID: 8272421.