WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 563128

CAS#: 27031-00-1

Description: iGP-1 is a cell-permeable inhibitor of mitochondrial sn-Glycerol 3-phosphate dehydrogenase (mGPDH).

Chemical Structure

CAS# 27031-00-1

Theoretical Analysis

MedKoo Cat#: 563128
Name: iGP-1
CAS#: 27031-00-1
Chemical Formula: C17H15N3O3
Exact Mass: 309.1113
Molecular Weight: 309.32
Elemental Analysis: C, 66.01; H, 4.89; N, 13.58; O, 15.52

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: iGP-1; iGP 1; iGP1;

IUPAC/Chemical Name: N-[4-(1H-Benzoimidazol-2-yl)-phenyl]-succinamic acid


InChi Code: InChI=1S/C17H15N3O3/c21-15(9-10-16(22)23)18-12-7-5-11(6-8-12)17-19-13-3-1-2-4-14(13)20-17/h1-8H,9-10H2,(H,18,21)(H,19,20)(H,22,23)


Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

Preparing Stock Solutions

The following data is based on the product molecular weight 309.32 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

Molarity Calculator

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1: Kajiyama S, Imai S, Hashimoto Y, Yamane C, Miyawaki T, Matsumoto S, Ozasa N, Tanaka M, Kajiyama S, Fukui M. Divided consumption of late-night-dinner improves glucose excursions in young healthy women: A randomized cross-over clinical trial. Diabetes Res Clin Pract. 2018 Feb;136:78-84. doi: 10.1016/j.diabres.2017.11.033. Epub 2017 Dec 1. PubMed PMID: 29199002.

2: Orr AL, Ashok D, Sarantos MR, Ng R, Shi T, Gerencser AA, Hughes RE, Brand MD. Novel inhibitors of mitochondrial sn-glycerol 3-phosphate dehydrogenase. PLoS One. 2014 Feb 24;9(2):e89938. doi: 10.1371/journal.pone.0089938. eCollection 2014. PubMed PMID: 24587137; PubMed Central PMCID: PMC3933693.

3: Swida U, Lucka L, Kress H. Glue protein genes in Drosophila virilis: their organization, developmental control of transcription and specific mRNA degradation. Development. 1990 Feb;108(2):269-80. PubMed PMID: 2351069.