Calcium methyltetrahydrofolate
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MedKoo CAT#: 597174

CAS#: 26560-38-3 (calcium)

Description: Calcium methyltetrahydrofolate is a synthetic derivative of folic acid, the predominant, naturally occurring form of folate. It is synthesized by reduction of folic acid to tetrahydrofolic acid followed by methylation and diastereoselective crystallization (in water) of L-5-MTHF as its calcium salt.


Chemical Structure

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Calcium methyltetrahydrofolate
CAS# 26560-38-3 (calcium)

Theoretical Analysis

MedKoo Cat#: 597174
Name: Calcium methyltetrahydrofolate
CAS#: 26560-38-3 (calcium)
Chemical Formula: C20H24CaN7O6
Exact Mass:
Molecular Weight: 498.53
Elemental Analysis: C, 48.19; H, 4.85; Ca, 8.04; N, 19.67; O, 19.26

Price and Availability

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300.0mg USD 520.0 2 Weeks
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Related CAS #: 134-35-0 (free acid)   26560-38-3 (calcium)  

Synonym: Calcium methyltetrahydrofolate; NSC 173328; NSC-173328; NSC173328;

IUPAC/Chemical Name: monocalcium mono((2S)-2-(4-(((2-amino-5-methyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl)methyl)amino)benzamido)-4-carboxybutanoate)

InChi Key: VWBBRFHSPXRJQD-ZEDZUCNESA-M

InChi Code: InChI=1S/C20H25N7O6.Ca/c1-27-12(9-23-16-15(27)18(31)26-20(21)25-16)8-22-11-4-2-10(3-5-11)17(30)24-13(19(32)33)6-7-14(28)29;/h2-5,12-13,22H,6-9H2,1H3,(H,24,30)(H,28,29)(H,32,33)(H4,21,23,25,26,31);/q;+2/p-1/t12?,13-;/m0./s1

SMILES Code: O=C(O)CC[C@@H](C([O-])=O)NC(C1=CC=C(NCC2N(C)C3=C(NC(N)=NC3=O)NC2)C=C1)=O.[Ca+2]

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

Preparing Stock Solutions

The following data is based on the product molecular weight 498.53 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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