Calcium dextrofolinate

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MedKoo CAT#: 597160

CAS#: 115940-48-2

Description: Calcium dextrofolinate is the calcium salt of a derivative of Folic Acid, a vitamin needed to synthesize DNA, conduct DNA repair and methylate DNA, it also acts as a cofactor in biological reactions involving folate. Levoleucovorin impurity.

Chemical Structure

Calcium dextrofolinate
CAS# 115940-48-2

Theoretical Analysis

MedKoo Cat#: 597160
Name: Calcium dextrofolinate
CAS#: 115940-48-2
Chemical Formula: C20H22CaN7O7
Exact Mass:
Molecular Weight: 512.51
Elemental Analysis: C, 46.87; H, 4.33; Ca, 7.82; N, 19.13; O, 21.85

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: Calcium dextrofolinate; Calcium (6R)-folinate;

IUPAC/Chemical Name: monocalcium mono((S)-2-(4-((((R)-2-amino-5-formyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl)methyl)amino)benzamido)-4-carboxybutanoate)


InChi Code: InChI=1S/C20H23N7O7.Ca/c21-20-25-16-15(18(32)26-20)27(9-28)12(8-23-16)7-22-11-3-1-10(2-4-11)17(31)24-13(19(33)34)5-6-14(29)30;/h1-4,9,12-13,22H,5-8H2,(H,24,31)(H,29,30)(H,33,34)(H4,21,23,25,26,32);/q;+2/p-1/t12-,13+;/m1./s1

SMILES Code: O=C(O)CC[C@@H](C([O-])=O)NC(C1=CC=C(NC[C@H]2N(C=O)C3=C(N=C(N)NC3=O)NC2)C=C1)=O.[Ca+2]

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

Preparing Stock Solutions

The following data is based on the product molecular weight 512.51 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Shen SJ, Zeng S. [Direct resolution of calcium folinate stereoisomers using a bovine serum albumin chiral HPLC column]. Zhejiang Da Xue Xue Bao Yi Xue Ban. 2004 Jan;33(1):11-4. Chinese. PubMed PMID: 14966932.