Captafol
featured

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 558337

CAS#: 2425-06-1

Description: Captafol is a fungicide. It is used to control almost all fungal diseases of plants except powdery mildews.


Chemical Structure

img
Captafol
CAS# 2425-06-1

Theoretical Analysis

MedKoo Cat#: 558337
Name: Captafol
CAS#: 2425-06-1
Chemical Formula: C10H9Cl4NO2S
Exact Mass: 346.91
Molecular Weight: 349.05
Elemental Analysis: C, 34.41; H, 2.60; Cl, 40.62; N, 4.01; O, 9.17; S, 9.19

Price and Availability

Size Price Availability Quantity
250.0mg USD 205.0 2 Weeks
Bulk inquiry

Synonym: Captafol; Difolatan; Difolatan 4F; Difolatan 4F1; Difolatan 80W;

IUPAC/Chemical Name: 1H-Isoindole-1,3(2H)-dione, 3a,4,7,7a-tetrahydro-2-((1,1,2,2-tetrachloroethyl)thio)-

InChi Key: JHRWWRDRBPCWTF-UHFFFAOYSA-N

InChi Code: InChI=1S/C10H9Cl4NO2S/c11-9(12)10(13,14)18-15-7(16)5-3-1-2-4-6(5)8(15)17/h1-2,5-6,9H,3-4H2

SMILES Code: O=C1N(SC(Cl)(Cl)C(Cl)Cl)C(C2CC=CCC12)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 349.05 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

1: Moreira RA, da Silva Mansano A, Rocha O. The toxicity of carbofuran to the freshwater rotifer, Philodina roseola. Ecotoxicology. 2015 Apr;24(3):604-15. doi: 10.1007/s10646-014-1408-2. Epub 2015 Jan 15. PubMed PMID: 25588673.

2: Onunga DO, Kowino IO, Ngigi AN, Osogo A, Orata F, Getenga ZM, Were H. Biodegradation of carbofuran in soils within Nzoia River Basin, Kenya. J Environ Sci Health B. 2015;50(6):387-97. doi: 10.1080/03601234.2015.1011965. PubMed PMID: 25844859.

3: Nguyen TP, Helbling DE, Bers K, Fida TT, Wattiez R, Kohler HP, Springael D, De Mot R. Genetic and metabolic analysis of the carbofuran catabolic pathway in Novosphingobium sp. KN65.2. Appl Microbiol Biotechnol. 2014 Oct;98(19):8235-52. doi: 10.1007/s00253-014-5858-5. Epub 2014 Jun 17. PubMed PMID: 24931307.

4: Ibrahim AT, Harabawy AS. Sublethal toxicity of carbofuran on the African catfish Clarias gariepinus: Hormonal, enzymatic and antioxidant responses. Ecotoxicol Environ Saf. 2014 Aug;106:33-9. doi: 10.1016/j.ecoenv.2014.04.032. Epub 2014 May 14. PubMed PMID: 24836875.

5: Campos-Garcia J, Martinez DS, Alves OL, Leonardo AF, Barbieri E. Ecotoxicological effects of carbofuran and oxidised multiwalled carbon nanotubes on the freshwater fish Nile tilapia: nanotubes enhance pesticide ecotoxicity. Ecotoxicol Environ Saf. 2015 Jan;111:131-7. doi: 10.1016/j.ecoenv.2014.10.005. Epub 2014 Oct 22. PubMed PMID: 25450925.

6: Jemutai-Kimosop S, Orata FO, K'Owino IO, Getenga ZM. The dissipation of carbofuran in two soils with different pesticide application histories within Nzoia River Drainage Basin, Kenya. Bull Environ Contam Toxicol. 2014 May;92(5):616-20. doi: 10.1007/s00128-014-1234-5. Epub 2014 Feb 28. PubMed PMID: 24577789.

7: Gbadegesin MA, Owumi SE, Akinseye V, Odunola OA. Evaluation of hepatotoxicity and clastogenicity of carbofuran in male Wistar rats. Food Chem Toxicol. 2014 Mar;65:115-9. doi: 10.1016/j.fct.2013.12.034. Epub 2013 Dec 28. PubMed PMID: 24380753.

8: Zhang CP, He HM, Yu JZ, Hu XQ, Zhu YH, Wang Q. Residues of carbosulfan and its metabolites carbofuran and 3-hydroxy carbofuran in rice field ecosystem in China. J Environ Sci Health B. 2016;51(6):351-7. doi: 10.1080/03601234.2015.1120606. Epub 2016 Mar 10. PubMed PMID: 26963425.

9: Ferreira RC, Papini S, de Andréa MM. Bioavailability and influence of ¹⁴C-carbofuran on Eisenia andrei avoidance, growth and reproduction in treated natural tropical soils. J Environ Sci Health B. 2015;50(4):266-74. doi: 10.1080/03601234.2015.999599. PubMed PMID: 25714458.

10: Sakunthala Tennakoon DA, Karunarathna WD, Udugampala US. Carbofuran concentrations in blood, bile and tissues in fatal cases of homicide and suicide. Forensic Sci Int. 2013 Apr 10;227(1-3):106-10. doi: 10.1016/j.forsciint.2012.10.039. Epub 2012 Nov 20. PubMed PMID: 23176810.

11: Harabawy AS, Ibrahim AT. Sublethal toxicity of carbofuran pesticide on the African catfish Clarias gariepinus (Burchell, 1822): hematological, biochemical and cytogenetic response. Ecotoxicol Environ Saf. 2014 May;103:61-7. doi: 10.1016/j.ecoenv.2013.09.022. Epub 2014 Jan 22. PubMed PMID: 24461394.

12: Clasen B, Leitemperger J, Murussi C, Pretto A, Menezes C, Dalabona F, Marchezan E, Adaime MB, Zanella R, Loro VL. Carbofuran promotes biochemical changes in carp exposed to rice field and laboratory conditions. Ecotoxicol Environ Saf. 2014 Mar;101:77-82. doi: 10.1016/j.ecoenv.2013.12.012. Epub 2014 Jan 11. PubMed PMID: 24507130.

13: Saxena PN, Gupta SK, Murthy RC. Comparative toxicity of carbaryl, carbofuran, cypermethrin and fenvalerate in Metaphire posthuma and Eisenia fetida -a possible mechanism. Ecotoxicol Environ Saf. 2014 Feb;100:218-25. doi: 10.1016/j.ecoenv.2013.11.006. Epub 2013 Dec 7. PubMed PMID: 24321850.

14: Mountacer H, Atifi A, Wong-Wah-Chung P, Sarakha M. Degradation of the pesticide carbofuran on clay and soil surfaces upon sunlight exposure. Environ Sci Pollut Res Int. 2014 Mar;21(5):3443-51. doi: 10.1007/s11356-013-2309-2. Epub 2013 Nov 17. PubMed PMID: 24243162.

15: Grawe GF, de Oliveira TR, de Andrade Narciso E, Moccelini SK, Terezo AJ, Soares MA, Castilho M. Electrochemical biosensor for carbofuran pesticide based on esterases from Eupenicillium shearii FREI-39 endophytic fungus. Biosens Bioelectron. 2015 Jan 15;63:407-413. doi: 10.1016/j.bios.2014.07.069. Epub 2014 Aug 2. PubMed PMID: 25127475.

16: Chin-Pampillo JS, Ruiz-Hidalgo K, Masís-Mora M, Carazo-Rojas E, Rodríguez-Rodríguez CE. Design of an optimized biomixture for the degradation of carbofuran based on pesticide removal and toxicity reduction of the matrix. Environ Sci Pollut Res Int. 2015 Dec;22(23):19184-93. doi: 10.1007/s11356-015-5093-3. Epub 2015 Aug 7. PubMed PMID: 26250812.

17: Mohiddin GJ, Srinivasulu M, Maddela NR, Manjunatha B, Rangaswamy V, Koch Kaiser AR, Maisincho Asqui JC, Darwin Rueda O. Influence of the insecticides acetamiprid and carbofuran on arylamidase and myrosinase activities in the tropical black and red clay soils. Environ Monit Assess. 2015 Jun;187(6):388. doi: 10.1007/s10661-015-4631-2. Epub 2015 May 30. PubMed PMID: 26024750.

18: Ensibi C, Hernández-Moreno D, Míguez Santiyán MP, Daly Yahya MN, Rodríguez FS, Pérez-López M. Effects of carbofuran and deltamethrin on acetylcholinesterase activity in brain and muscle of the common carp. Environ Toxicol. 2014 Apr;29(4):386-93. doi: 10.1002/tox.21765. Epub 2012 Mar 16. PubMed PMID: 22422543.

19: Mansano AS, Moreira RA, Pierozzi M, Oliveira TMA, Vieira EM, Rocha O, Regali-Seleghim MH. Effects of diuron and carbofuran pesticides in their pure and commercial forms on Paramecium caudatum: The use of protozoan in ecotoxicology. Environ Pollut. 2016 Jun;213:160-172. doi: 10.1016/j.envpol.2015.11.054. Epub 2016 Feb 16. PubMed PMID: 26890484.

20: Morales J, Manso JA, Cid A, Mejuto JC. Degradation of carbofuran and carbofuran-derivatives in presence of humic substances under basic conditions. Chemosphere. 2012 Nov;89(11):1267-71. doi: 10.1016/j.chemosphere.2012.05.018. Epub 2012 Jun 18. PubMed PMID: 22717164.

Captafol

250.0mg / USD 205.0