VU0071063
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 563099

CAS#: 333415-38-6

Description: VU0071063 is an activator of Kir6.2/SUR1.


Chemical Structure

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VU0071063
CAS# 333415-38-6

Theoretical Analysis

MedKoo Cat#: 563099
Name: VU0071063
CAS#: 333415-38-6
Chemical Formula: C18H22N4O2
Exact Mass: 326.1743
Molecular Weight: 326.4
Elemental Analysis: C, 66.24; H, 6.79; N, 17.17; O, 9.80

Price and Availability

Size Price Availability Quantity
5.0mg USD 260.0 2 Weeks
10.0mg USD 440.0 2 Weeks
25.0mg USD 790.0 2 Weeks
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Synonym: VU0071063; VU-0071063; VU 0071063;

IUPAC/Chemical Name: 7-(4-(tert-Butyl)benzyl)-1,3-dimethyl-1H-purine-2,6(3H,7H)-dione

InChi Key: ZFZAIHKQJBMYLO-UHFFFAOYSA-N

InChi Code: InChI=1S/C18H22N4O2/c1-18(2,3)13-8-6-12(7-9-13)10-22-11-19-15-14(22)16(23)21(5)17(24)20(15)4/h6-9,11H,10H2,1-5H3

SMILES Code: O=C(N1C)N(C)C2=C(N(CC3=CC=C(C(C)(C)C)C=C3)C=N2)C1=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 326.4 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Raphemot R, Swale DR, Dadi PK, Jacobson DA, Cooper P, Wojtovich AP, Banerjee S, Nichols CG, Denton JS. Direct activation of β-cell KATP channels with a novel xanthine derivative. Mol Pharmacol. 2014 Jun;85(6):858-65. doi: 10.1124/mol.114.091884. Epub 2014 Mar 19. PubMed PMID: 24646456; PubMed Central PMCID: PMC4014665.