WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 563080
Description: alpha-RA-F is a modulator of collagen synthesis and matrix metalloproteinases (MMPs) expression levels. It acts by boosting collagen synthesis and reducing MMPs expression levels in human fibroblasts without cytotoxicity.
MedKoo Cat#: 563080
Chemical Formula: C16H16N2O4
Exact Mass: 300.111
Molecular Weight: 300.31
Elemental Analysis: C, 63.99; H, 5.37; N, 9.33; O, 21.31
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
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Synonym: alpha-RA-F; alpha RA F; alphaRAF; α-RA-F; α RA F; αRAF;
IUPAC/Chemical Name: (S)-N-(1-amino-1-oxo-3-phenylpropan-2-yl)-3,5-dihydroxybenzamide
InChi Key: VIBGZWUSHYPKCT-AWEZNQCLSA-N
InChi Code: InChI=1S/C16H16N2O4/c17-15(21)14(6-10-4-2-1-3-5-10)18-16(22)11-7-12(19)9-13(20)8-11/h1-5,7-9,14,19-20H,6H2,(H2,17,21)(H,18,22)/t14-/m0/s1
SMILES Code: OC1=CC(C(N[C@H](C(N)=O)CC2=CC=CC=C2)=O)=CC(O)=C1
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 300.31 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Kwak SY, Noh JM, Lee S, Lee SH, Jeon SJ, Kim HI, Kim JH, Lee YS. Effect of alpha-resorcylic acid-L-phenylalanine amide on collagen synthesis and matrix metalloproteinase expression in fibroblasts. Bioorg Med Chem Lett. 2014 Feb 1;24(3):742-5. doi: 10.1016/j.bmcl.2013.12.110. Epub 2014 Jan 3. PubMed PMID: 24411126.