alpha-RA-F

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 563080

CAS#: 1260239-23-3

Description: alpha-RA-F is a modulator of collagen synthesis and matrix metalloproteinases (MMPs) expression levels. It acts by boosting collagen synthesis and reducing MMPs expression levels in human fibroblasts without cytotoxicity.


Chemical Structure

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alpha-RA-F
CAS# 1260239-23-3

Theoretical Analysis

MedKoo Cat#: 563080
Name: alpha-RA-F
CAS#: 1260239-23-3
Chemical Formula: C16H16N2O4
Exact Mass: 300.111
Molecular Weight: 300.31
Elemental Analysis: C, 63.99; H, 5.37; N, 9.33; O, 21.31

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: alpha-RA-F; alpha RA F; alphaRAF; α-RA-F; α RA F; αRAF;

IUPAC/Chemical Name: (S)-N-(1-amino-1-oxo-3-phenylpropan-2-yl)-3,5-dihydroxybenzamide

InChi Key: VIBGZWUSHYPKCT-AWEZNQCLSA-N

InChi Code: InChI=1S/C16H16N2O4/c17-15(21)14(6-10-4-2-1-3-5-10)18-16(22)11-7-12(19)9-13(20)8-11/h1-5,7-9,14,19-20H,6H2,(H2,17,21)(H,18,22)/t14-/m0/s1

SMILES Code: OC1=CC(C(N[C@H](C(N)=O)CC2=CC=CC=C2)=O)=CC(O)=C1

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 300.31 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Kwak SY, Noh JM, Lee S, Lee SH, Jeon SJ, Kim HI, Kim JH, Lee YS. Effect of alpha-resorcylic acid-L-phenylalanine amide on collagen synthesis and matrix metalloproteinase expression in fibroblasts. Bioorg Med Chem Lett. 2014 Feb 1;24(3):742-5. doi: 10.1016/j.bmcl.2013.12.110. Epub 2014 Jan 3. PubMed PMID: 24411126.