2-Iodobenzenamine

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 591654

CAS#: 615-43-0

Description: 2-Iodobenzenamine is a biochemical.

Chemical Structure

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2-Iodobenzenamine
CAS# 615-43-0
Instruction

Theoretical Analysis

MedKoo Cat#: 591654
Name: 2-Iodobenzenamine
CAS#: 615-43-0
Chemical Formula: C6H6IN
Exact Mass: 218.95
Molecular Weight: 219.030
Elemental Analysis: C, 32.90; H, 2.76; I, 57.94; N, 6.40

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym: 2-Iodobenzenamine; NSC 34544; NSC-34544; NSC34544

IUPAC/Chemical Name: 2-Iodoaniline

InChi Key: UBPDKIDWEADHPP-UHFFFAOYSA-N

InChi Code: InChI=1S/C6H6IN/c7-5-3-1-2-4-6(5)8/h1-4H,8H2

SMILES Code: NC1=CC=CC=C1I

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 219.03 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Yin B, Zhang X, Zhang X, Peng H, Zhou W, Liu B, Jiang H. Access to polysubstituted indoles or benzothiophenes via palladium-catalyzed cross-coupling of furfural tosylhydrazones with 2-iodoanilines or 2-iodothiophenols. Chem Commun (Camb). 2015 Apr 11;51(28):6126-9. doi: 10.1039/c5cc00267b. PubMed PMID: 25743623.

2: Melzer B, Plodek A, Bracher F. Total synthesis of the marine pyridoacridine alkaloid demethyldeoxyamphimedine. J Org Chem. 2014 Aug 1;79(15):7239-42. doi: 10.1021/jo501312d. Epub 2014 Jul 18. PubMed PMID: 25081029.

3: Iwasaki H, Suzuki K, Yamane M, Yoshida S, Kojima N, Ozeki M, Yamashita M. Indole synthesis from N-allenyl-2-iodoanilines under mild conditions mediated by samarium(II) diiodide. Org Biomol Chem. 2014 Sep 21;12(35):6812-5. doi: 10.1039/c4ob01164c. PubMed PMID: 25072695.

4: Jones C, Nguyen Q, Driver TG. Dirhodium(II) carboxylate catalyzed formation of 1,2,3-trisubstituted indoles from styryl azides. Angew Chem Int Ed Engl. 2014 Jan 13;53(3):785-8. doi: 10.1002/anie.201308611. Epub 2013 Nov 26. PubMed PMID: 24281835.

5: Phetrak N, Rukkijakan T, Sirijaraensre J, Prabpai S, Kongsaeree P, Klinchan C, Chuawong P. Regioselectivity of Larock heteroannulation: a contribution from electronic properties of diarylacetylenes. J Org Chem. 2013 Dec 20;78(24):12703-9. doi: 10.1021/jo402304s. Epub 2013 Dec 5. PubMed PMID: 24279463.

6: Xiang SK, Tan W, Zhang DX, Tian XL, Feng C, Wang BQ, Zhao KQ, Hu P, Yang H. Synthesis of benzimidazoles by potassium tert-butoxide-promoted intermolecular cyclization reaction of 2-iodoanilines with nitriles. Org Biomol Chem. 2013 Nov 14;11(42):7271-5. doi: 10.1039/c3ob41479e. PubMed PMID: 24081201.

7: Omote M, Tanaka M, Tanaka M, Ikeda A, Tarui A, Sato K, Ando A. Synthesis of 2-aryl-3-trifluoromethylquinolines using (E)-trimethyl(3,3,3-trifluoroprop-1-enyl)silane. J Org Chem. 2013 Jun 21;78(12):6196-201. doi: 10.1021/jo400859s. Epub 2013 Jun 4. PubMed PMID: 23705690.

8: Okuro K, Alper H. Palladium-catalyzed intermolecular cyclocarbonylation of 2-iodoanilines with the Michael acceptor, diethyl ethoxycarbonylbutendienoate. J Org Chem. 2012 May 4;77(9):4420-4. doi: 10.1021/jo300173g. Epub 2012 Apr 26. PubMed PMID: 22480192.

9: Cao J, Xu Y, Kong Y, Cui Y, Hu Z, Wang G, Deng Y, Lai G. Synthesis of δ-carbolines via a Pd-catalyzed sequential reaction from 2-iodoanilines and N-tosyl-enynamines. Org Lett. 2012 Jan 6;14(1):38-41. doi: 10.1021/ol2027762. Epub 2011 Nov 30. PubMed PMID: 22126429.

10: Ding Q, He X, Wu J. Synthesis of 2-aminobenzothiazole via copper(I)-catalyzed tandem reaction of 2-iodobenzenamine with isothiocyanate. J Comb Chem. 2009 Jul-Aug;11(4):587-91. doi: 10.1021/cc900027c. PubMed PMID: 19449803.