IDE 2
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 563061

CAS#: 1136466-93-7

Description: IDE 2 is a TGF-β activator.


Chemical Structure

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IDE 2
CAS# 1136466-93-7

Theoretical Analysis

MedKoo Cat#: 563061
Name: IDE 2
CAS#: 1136466-93-7
Chemical Formula: C12H20N2O3
Exact Mass: 240.1474
Molecular Weight: 240.3
Elemental Analysis: C, 59.98; H, 8.39; N, 11.66; O, 19.97

Price and Availability

Size Price Availability Quantity
5.0mg USD 290.0 2 Weeks
10.0mg USD 460.0 2 Weeks
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Synonym: IDE 2; IDE2; IDE-2; Induce Definitive Endoderm;

IUPAC/Chemical Name: 7-(2-cyclopentylidenehydrazinyl)-7-oxoheptanoic acid

InChi Key: CVYPYYPTFNVREL-UHFFFAOYSA-N

InChi Code: InChI=1S/C12H20N2O3/c15-11(8-2-1-3-9-12(16)17)14-13-10-6-4-5-7-10/h1-9H2,(H,14,15)(H,16,17)

SMILES Code: OC(CCCCCC(N/N=C1CCCC\1)=O)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 240.3 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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Reconstitution Calculator

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1: Nazarenko AY. Crystal structure of strontium and barium acesulafame (6-methyl-4-oxo-4H-1,2,3-oxa-thia-zin-3-ide 2,2-dioxide). Acta Crystallogr E Crystallogr Commun. 2018 Apr 24;74(Pt 5):698-702. doi: 10.1107/S2056989018006059. eCollection 2018 May 1. PubMed PMID: 29850095; PubMed Central PMCID: PMC5947491.

2: Gerhardt V, Bolte M. 6-Chloroisocytosine and 5-bromo-6-methylisocytosine: again, one or two tautomers present in the same crystal? Acta Crystallogr C Struct Chem. 2016 Jan;72(Pt 1):84-93. doi: 10.1107/S2053229615024080. Epub 2016 Jan 1. PubMed PMID: 26742833.

3: Diekmann U, Naujok O, Blasczyk R, Müller T. Embryonic stem cells of the non-human primate Callithrix jacchus can be differentiated into definitive endoderm by Activin-A but not IDE-1/2. J Tissue Eng Regen Med. 2015 Apr;9(4):473-9. doi: 10.1002/term.1709. Epub 2013 Feb 18. PubMed PMID: 23418163.

4: Bolarinwa OA, Adeola O. Energy value of wheat, barley, and wheat dried distillers grains with solubles for broiler chickens determined using the regression method. Poult Sci. 2012 Aug;91(8):1928-35. doi: 10.3382/ps.2012-02261. PubMed PMID: 22802187.

5: Cuesta-Vargas A, Gonzaleaz-Sanchez M, Farasyn A. Development of a Spanish version of the "Backache Index". J Back Musculoskelet Rehabil. 2010;23(3):105-10. doi: 10.3233/BMR-2010-0256. PubMed PMID: 20858939.

6: Benedetti M, Tamasi G, Cini R, Natile G. X-ray structure and circular dichroism of pure rotamers of bis[guanosine-5'-monophosphate(-1)](N,N,N',N'-tetramethylcyclohexyl-1,2-diamine)p latinum(II) complexes that have R,R and S,S configurations at the asymmetric diamine. Chemistry. 2003 Dec 15;9(24):6122-32. PubMed PMID: 14679524.

7: Wolpert E, Franksson L, Kärre K. Dominant and cryptic antigens in the MHC class I restricted T cell response across a complex minor histocompatibility barrier: analysis and mapping by elution of cellular peptides. Int Immunol. 1995 Jun;7(6):919-28. PubMed PMID: 7577800.

8: Jain RK, Piskorz CF, Matta KL. A facile synthesis of nitrophenyl oligosaccharides containing the O-alpha-L-fucopyranosyl-(1----3)-2-acetamido-2-deoxy-beta-D-glucopyrano syl unit at their nonreducing end. Carbohydr Res. 1992 Apr 10;228(1):243-53. PubMed PMID: 1516089.

9: Pool J. Hospital management: integrating the dual hierarchy? Int J Health Plann Manage. 1991 Jul-Sep;6(3):193-207. PubMed PMID: 10116623.

IDE 2

5.0mg / USD 290.0