Gloxazone
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MedKoo CAT#: 558188

CAS#: 2507-91-7

Description: Gloxazone is an effective but toxic anaplasmacide.


Chemical Structure

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Gloxazone
CAS# 2507-91-7

Theoretical Analysis

MedKoo Cat#: 558188
Name: Gloxazone
CAS#: 2507-91-7
Chemical Formula: C8H16N6OS2
Exact Mass: 276.08
Molecular Weight: 276.380
Elemental Analysis: C, 34.77; H, 5.84; N, 30.41; O, 5.79; S, 23.20

Price and Availability

Size Price Availability Quantity
5mg USD 90 Ready to ship
10mg USD 150 Ready to ship
25mg USD 250 Ready to ship
50mg USD 450 Ready to ship
100mg USD 750 Ready to ship
200mg USD 1350 Ready to ship
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Synonym: 356C61; BW 356C61; BW356C61; BW-356C61; Contrapar; Gloxazon; Gloxazone; NSC 82116; NSC-82116; NSC82116; U 7726; U-7726; U7726; WR 9838; WR9838; WR-9838;

IUPAC/Chemical Name: Butyraldehyde, 3-ethoxy-2-oxo-, bis(thiosemicarbazone)

InChi Key: ARIFZLJIERKKEL-SNNHKCHZSA-N

InChi Code: InChI=1S/C8H16N6OS2/c1-3-15-5(2)6(12-14-8(10)17)4-11-13-7(9)16/h4-5H,3H2,1-2H3,(H3,9,13,16)(H3,10,14,17)/b11-4+,12-6-

SMILES Code: CC(OCC)C(/C=N/NC(N)=S)=N\NC(N)=S

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 276.38 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: McHardy N, Berger J, Taylor RJ, Farebrother D, James JA. Comparison of gloxazone, an effective but toxic anaplasmacide, with imidocarb dihydrochloride. Res Vet Sci. 1980 Sep;29(2):198-202. PubMed PMID: 6451008.

2: Du Plessis JL. The influence of dithiosemicarbazone on the immunity of sheep to heartwater. Onderstepoort J Vet Res. 1981 Sep;48(3):175-6. PubMed PMID: 7335333.

3: Du Plessis JL, Berche P, Van Gas L. T cell-mediated immunity to Cowdria ruminantium in mice: the protective role of Lyt-2+ T cells. Onderstepoort J Vet Res. 1991 Sep;58(3):171-9. PubMed PMID: 1923379.

4: Wassink LA, Franssen FF, Uilenberg G, Perié NM. Observations on mouse-infective stocks of Cowdria ruminantium: attempts to demonstrate persistence of the organism in mice immune to the Kwanyanga stock. Res Vet Sci. 1987 Jan;42(1):65-7. PubMed PMID: 2950579.