WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 563045
Description: YLT205 is an inducer of apoptosis in human colorectal cells via the mitochondrial apoptosis pathway. It also acts by inhibiting tumor growth.
MedKoo Cat#: 563045
Chemical Formula: C16H12BrClN4O2S2
Exact Mass: 469.9274
Molecular Weight: 471.77
Elemental Analysis: C, 40.73; H, 2.56; Br, 16.94; Cl, 7.51; N, 11.88; O, 6.78; S, 13.59
This product is not in stock, which may be available by custom synthesis.
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Synonym: YLT205; YLT-205; YLT 205;
IUPAC/Chemical Name: N-(5-Bromopyridin-2-yl)-2-((6-(2-chloroacetamido)benzo[d]thiazol-2-yl)thio)acetamide
InChi Key: QKMMRERCAFXACY-UHFFFAOYSA-N
InChi Code: InChI=1S/C16H12BrClN4O2S2/c17-9-1-4-13(19-7-9)22-15(24)8-25-16-21-11-3-2-10(5-12(11)26-16)20-14(23)6-18/h1-5,7H,6,8H2,(H,20,23)(H,19,22,24)
SMILES Code: O=C(NC1=NC=C(Br)C=C1)CSC2=NC3=CC=C(NC(CCl)=O)C=C3S2
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 471.77 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Zhu Y, Xia Y, Ye T, Shi X, Song X, Liu L, Zeng J, Wang N, Luo Y, Han Y, Yu L. A novel small-molecule YLT205 induces apoptosis in human colorectal cells via mitochondrial apoptosis pathway in vitro and inhibits tumor growth in vivo. Cell Physiol Biochem. 2014;33(4):933-44. doi: 10.1159/000358665. Epub 2014 Mar 31. PubMed PMID: 24713812.