WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 563034
Description: R24 is a potent regulator of angiogenesis and ROS production.
MedKoo Cat#: 563034
Chemical Formula: C19H16O6
Exact Mass: 340.0947
Molecular Weight: 340.33
Elemental Analysis: C, 67.06; H, 4.74; O, 28.21
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.
Synonym: R24; R-24; R 24;
IUPAC/Chemical Name: 3,6-bis(oxiran-2-ylmethoxy)-9H-xanthen-9-one
InChi Key: UZQSJQFHCZAIQQ-UHFFFAOYSA-N
InChi Code: InChI=1S/C19H16O6/c20-19-15-3-1-11(21-7-13-9-23-13)5-17(15)25-18-6-12(2-4-16(18)19)22-8-14-10-24-14/h1-6,13-14H,7-10H2
SMILES Code: O=C1C2=C(C=C(OCC3OC3)C=C2)OC4=C1C=CC(OCC5CO5)=C4
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 340.33 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Wang L, Bhatta A, Toque HA, Rojas M, Yao L, Xu Z, Patel C, Caldwell RB, Caldwell RW. Arginase inhibition enhances angiogenesis in endothelial cells exposed to hypoxia. Microvasc Res. 2015 Mar;98:1-8. doi: 10.1016/j.mvr.2014.11.002. Epub 2014 Nov 7. PubMed PMID: 25445030; PubMed Central PMCID: PMC4361269.
2: Zhang M, Liu C, Zhang Z, Yang S, Zhang B, Yin L, Swarts S, Vidyasagar S, Zhang L, Okunieff P. A new flavonoid regulates angiogenesis and reactive oxygen species production. Adv Exp Med Biol. 2014;812:149-155. doi: 10.1007/978-1-4939-0620-8_20. PubMed PMID: 24729227.