WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 533017

CAS#: Unknown

Description: M090 is a potent inhibitor against amantadine-resistant viruses, including the 2009 H1N1 pandemic strains, and oseltamivir-resistant viruses. M090 targets influenza HA and it occupied a highly conserved pocket of the HA2 domain and inhibited virus-mediated membrane fusion by "locking" the bending state of HA2 during the conformational rearrangement process.

Chemical Structure

CAS# Unknown

Theoretical Analysis

MedKoo Cat#: 533017
Name: M090
CAS#: Unknown
Chemical Formula: C18H28N2
Exact Mass: 272.2252
Molecular Weight: 272.436
Elemental Analysis: C, 79.36; H, 10.36; N, 10.28

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: M090; M-090; M 090.

IUPAC/Chemical Name: (1R,2R,3R,5S)-N-((3-cyclopropyl-1H-pyrrol-2-yl)methyl)-2,6,6-trimethylbicyclo[3.1.1]heptan-3-amine


InChi Code: InChI=1S/C18H28N2/c1-11-15-8-13(18(15,2)3)9-16(11)20-10-17-14(6-7-19-17)12-4-5-12/h6-7,11-13,15-16,19-20H,4-5,8-10H2,1-3H3/t11-,13+,15-,16-/m1/s1

SMILES Code: CC1(C)[C@H]2[C@@H](C)[C@H](NCC3=C(C4CC4)C=CN3)C[C@@H]1C2

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 272.436 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Zhao X, Li R, Zhou Y, Xiao M, Ma C, Yang Z, Zeng S, Du Q, Yang C, Jiang H, Hu Y, Wang K, Mok CKP, Sun P, Dong J, Cui W, Wang J, Tu Y, Yang Z, Hu W. Discovery of Highly Potent Pinanamine-Based Inhibitors against Amantadine- and Oseltamivir-Resistant Influenza A Viruses. J Med Chem. 2018 Jun 11. doi: 10.1021/acs.jmedchem.8b00042. [Epub ahead of print] PubMed PMID: 29799746.

2: Ong JJ, Rountrey AN, Zinke J, Meeuwig JJ, Grierson PF, O'Donnell AJ, Newman SJ, Lough JM, Trougan M, Meekan MG. Evidence for climate-driven synchrony of marine and terrestrial ecosystems in northwest Australia. Glob Chang Biol. 2016 Aug;22(8):2776-86. doi: 10.1111/gcb.13239. Epub 2016 Mar 11. PubMed PMID: 26970074.

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4: Larkan NJ, Ruzicka DR, Edmonds-Tibbett T, Durkin JM, Jackson LE, Smith FA, Schachtman DP, Smith SE, Barker SJ. The reduced mycorrhizal colonisation (rmc) mutation of tomato disrupts five gene sequences including the CYCLOPS/IPD3 homologue. Mycorrhiza. 2013 Oct;23(7):573-84. doi: 10.1007/s00572-013-0498-7. Epub 2013 Apr 10. PubMed PMID: 23572326.

5: McLean EH, Ludwig M, Grierson PF. Root hydraulic conductance and aquaporin abundance respond rapidly to partial root-zone drying events in a riparian Melaleuca species. New Phytol. 2011 Nov;192(3):664-75. doi: 10.1111/j.1469-8137.2011.03834.x. Epub 2011 Aug 16. PubMed PMID: 21848988.

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7: Atkins CA, Smith PM. Translocation in legumes: assimilates, nutrients, and signaling molecules. Plant Physiol. 2007 Jun;144(2):550-61. Review. PubMed PMID: 17556518; PubMed Central PMCID: PMC1914204.

8: McDonald JI, Coupland GT, Kendrick GA. Underwater video as a monitoring tool to detect change in seagrass cover. J Environ Manage. 2006 Jul;80(2):148-55. Epub 2005 Dec 13. PubMed PMID: 16359777.

9: Cullen LE, Macfarlane C. Comparison of cellulose extraction methods for analysis of stable-isotope ratios of carbon and oxygen in plant material. Tree Physiol. 2005 May;25(5):563-69. PubMed PMID: 15741154.

10: Macfarlane C, Hansen LD, Edwards J, White DA, Adams MA. Growth efficiency increases as relative growth rate increases in shoots and roots of Eucalyptus globulus deprived of nitrogen or treated with salt. Tree Physiol. 2005 May;25(5):571-82. PubMed PMID: 15741150.

11: Cawthray GR. An improved reversed-phase liquid chromatographic method for the analysis of low-molecular mass organic acids in plant root exudates. J Chromatogr A. 2003 Sep 5;1011(1-2):233-40. PubMed PMID: 14518781.