AHR-11797

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 591513

CAS#: 125992-09-8

Description: AHR-11797 is a novel benzodiazepine antagonist.


Chemical Structure

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AHR-11797
CAS# 125992-09-8

Theoretical Analysis

MedKoo Cat#: 591513
Name: AHR-11797
CAS#: 125992-09-8
Chemical Formula: C17H14N2O
Exact Mass: 262.11
Molecular Weight: 262.310
Elemental Analysis: C, 77.84; H, 5.38; N, 10.68; O, 6.10

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

Request quote for custom synthesis

Synonym:

IUPAC/Chemical Name: 3H-Pyrrolo(3,2,1-ij)quinazolin-3-one, 5,6-dihydro-6-methyl-1-phenyl-

InChi Key: DVLGLHMHWBPJKX-UHFFFAOYSA-N

InChi Code: InChI=1S/C17H14N2O/c1-11-10-19-16-13(11)8-5-9-14(16)15(18-17(19)20)12-6-3-2-4-7-12/h2-9,11H,10H2,1H3

SMILES Code: O=C1N2C3=C(C(C)C2)C=CC=C3C(C4=CC=CC=C4)=N1

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 262.31 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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1: Maguire PA, Mechanick JI, Davies MF, Ellis DM, Meredith DB, Loew GH. Resolving receptor heterogeneity using Fourier-derived affinity spectrum analysis and LIGAND: benzodiazepine receptors in the rat spinal cord. J Pharmacol Exp Ther. 1995 May;273(2):842-9. PubMed PMID: 7752088.

2: Davies MF, Onaivi ES, Chen SW, Maguire PA, Tsai NF, Loew GH. Evidence for central benzodiazepine receptor heterogeneity from behavior tests. Pharmacol Biochem Behav. 1994 Sep;49(1):47-56. PubMed PMID: 7816889.

3: Maguire PA, Villar HO, Davies MF, Loew GH. Thermodynamic analysis of binding to the cerebellar type I benzodiazepine receptor. Eur J Pharmacol. 1992 Jul 1;226(3):233-8. PubMed PMID: 1330631.

4: Wettstein JG. Effects of the novel benzodiazepine agonist quazepam on suppressed behavior of monkeys. Eur J Pharmacol. 1988 Oct 11;155(1-2):19-25. PubMed PMID: 2907488.